Reactome | mRNA decay by 3' to 5' exoribonuclease

Schema > Pathway > Entries

mRNA decay by 3' to 5' exoribonuclease Show undefined attributes

compartment	[Compartment:70101] cytosol
created	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
dbId	11107526
displayName	mRNA decay by 3' to 5' exoribonuclease
eventOf	[Pathway:R-SCE-429914] Deadenylation-dependent mRNA decay - Saccharomyces cerevisiae
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:22759] nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-SCE-430028] Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion - Saccharomyces cerevisiae [Reaction:R-SCE-429961] DCPS scavenges the 7-methylguanosine cap of mRNA - Saccharomyces cerevisiae
inferredFrom	[Pathway:R-HSA-429958] mRNA decay by 3' to 5' exoribonuclease - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	mRNA decay by 3' to 5' exoribonuclease
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68322] Saccharomyces cerevisiae
stId	R-SCE-429958
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SCE-429914] Deadenylation-dependent mRNA decay
(inferredTo)	[Pathway:R-HSA-429958] mRNA decay by 3' to 5' exoribonuclease

Cite Us!