Reactome | UBE2I (UBC9), PIAS1 SUMOylate FOXL2 with SUMO1

Schema > Reaction > Entries

UBE2I (UBC9), PIAS1 SUMOylate FOXL2 with SUMO1 Show undefined attributes

catalystActivity	[CatalystActivity:11094364] SUMO transferase activity of UBE2I,PIAS1 [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
dbId	11094366
displayName	UBE2I (UBC9), PIAS1 SUMOylate FOXL2 with SUMO1
eventOf	[Pathway:R-SCE-3232118] SUMOylation of transcription factors - Saccharomyces cerevisiae
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-3968414] UBE2I (UBC9), PIAS1 SUMOylate FOXL2 with SUMO1 - Homo sapiens
input	[DefinedSet:R-SCE-3968421-3] Homologues of FOXL2 [nucleoplasm] 3 × [Complex:R-SCE-2993783] SUMO1:C93-UBE2I [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	UBE2I (UBC9), PIAS1 SUMOylate FOXL2 with SUMO1
output	[DefinedSet:R-SCE-3968395-3] Homologues of monoSUMO1-K25,K114,K150-FOXL2 [nucleoplasm] 3 × [EntityWithAccessionedSequence:R-SCE-912481] UBC9 [nucleoplasm]
precedingEvent	[Reaction:R-SCE-2993780] Transfer of SUMO1 from E1 to UBE2I (UBC9) - Saccharomyces cerevisiae
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68322] Saccharomyces cerevisiae
stId	R-SCE-3968414
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SCE-3232118] SUMOylation of transcription factors
(inferredTo)	[Reaction:R-HSA-3968414] UBE2I (UBC9), PIAS1 SUMOylate FOXL2 with SUMO1

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