Reactome | Integrin signaling

Schema > Pathway > Entries

created	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
dbId	11107390
displayName	Integrin signaling
eventOf	[Pathway:R-SCE-76009] Platelet Aggregation (Plug Formation) - Saccharomyces cerevisiae [TopLevelPathway:R-SCE-162582] Signal Transduction - Saccharomyces cerevisiae
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-SCE-354173] Activation of Rap1 by cytosolic GEFs - Saccharomyces cerevisiae [Reaction:R-SCE-939265] Activation of Rap1 by membrane-associated GEFs - Saccharomyces cerevisiae
inferredFrom	[Pathway:R-HSA-354192] Integrin signaling - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Integrin signaling
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68322] Saccharomyces cerevisiae
stId	R-SCE-354192
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[TopLevelPathway:R-SCE-162582] Signal Transduction [Pathway:R-SCE-76009] Platelet Aggregation (Plug Formation)
(inferredTo)	[Pathway:R-HSA-354192] Integrin signaling