Reactome | HDMs demethylate histones

Schema > Pathway > Entries

created	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
dbId	11107880
displayName	HDMs demethylate histones
eventOf	[Pathway:R-SCE-3247509] Chromatin modifying enzymes - Saccharomyces cerevisiae
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-SCE-5423117] PHF8 demethylates MeK21-histone H4 - Saccharomyces cerevisiae
inferredFrom	[Pathway:R-HSA-3214842] HDMs demethylate histones - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	HDMs demethylate histones
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68322] Saccharomyces cerevisiae
stId	R-SCE-3214842
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-SCE-3247509] Chromatin modifying enzymes
(inferredTo)	[Pathway:R-HSA-3214842] HDMs demethylate histones

Cite Us!