Reactome | Cargo of TOM40 [cytosol]

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Cargo of TOM40 [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
consumedByEvent	[Reaction:R-SCE-1252255] TOM40:TOM70 complex translocates proteins from the cytosol to the mitochondrial intermembrane space - Saccharomyces cerevisiae
created	[InstanceEdit:1252211] May, B, 2011-04-27
dbId	1252224
displayName	Cargo of TOM40 [cytosol]
hasMember	[EntityWithAccessionedSequence:R-SCE-1252151] AAC1 [cytosol] - Saccharomyces cerevisiae [EntityWithAccessionedSequence:R-SCE-1252172] ATP9 precursor [cytosol] - Saccharomyces cerevisiae [EntityWithAccessionedSequence:R-SCE-1252120] ATP1 precursor [cytosol] - Saccharomyces cerevisiae [EntityWithAccessionedSequence:R-SCE-1252203] ATP2 precursor [cytosol] - Saccharomyces cerevisiae [EntityWithAccessionedSequence:R-SCE-1252111] ACO1 [cytosol] - Saccharomyces cerevisiae [EntityWithAccessionedSequence:R-SCE-1252092] CIT1 [cytosol] - Saccharomyces cerevisiae [EntityWithAccessionedSequence:R-SCE-1252090] CYT1 [cytosol] - Saccharomyces cerevisiae [EntityWithAccessionedSequence:R-SCE-1252153] HSP60 [cytosol] - Saccharomyces cerevisiae [EntityWithAccessionedSequence:R-SCE-1252188] IDH1 [cytosol] - Saccharomyces cerevisiae [EntityWithAccessionedSequence:R-SCE-1252168] BCS1 [cytosol] - Saccharomyces cerevisiae [EntityWithAccessionedSequence:R-SCE-1252169] TIM22 [cytosol] - Saccharomyces cerevisiae [EntityWithAccessionedSequence:R-SCE-1252094] TIM54 [cytosol] - Saccharomyces cerevisiae [EntityWithAccessionedSequence:R-SCE-1252146] TOM40 [cytosol] - Saccharomyces cerevisiae [EntityWithAccessionedSequence:R-SCE-1252093] CYB2 precursor [cytosol] - Saccharomyces cerevisiae [EntityWithAccessionedSequence:R-SCE-2457653] SSC1 [cytosol] - Saccharomyces cerevisiae
inDisease	false
inferredTo	[CandidateSet:R-HSA-1268006] Cargo of TOMM40 [cytosol] - Homo sapiens
literatureReference	[LiteratureReference:1252288] Roles of Tom70 in import of presequence-containing mitochondrial proteins [LiteratureReference:1252328] Apocytochrome c requires the TOM complex for translocation across the mitochondrial outer membrane [LiteratureReference:1252310] Mitochondrial protein import: recognition of internal import signals of BCS1 by the TOM complex [LiteratureReference:1252319] Biogenesis of Tim proteins of the mitochondrial carrier import pathway: differential targeting mechanisms and crossing over with the main import pathway [LiteratureReference:1252337] Protein import into yeast mitochondria is accelerated by the outer membrane protein MAS70 [LiteratureReference:1252323] A mitochondrial import receptor for the ADP/ATP carrier [LiteratureReference:1252314] Reconstituted TOM core complex and Tim9/Tim10 complex of mitochondria are sufficient for translocation of the ADP/ATP carrier across membranes [LiteratureReference:1252299] Mitochondrial import of the ADP/ATP carrier: the essential TIM complex of the intermembrane space is required for precursor release from the TOM complex [LiteratureReference:1252312] The import route of ADP/ATP carrier into mitochondria separates from the general import pathway of cleavable preproteins at the trans side of the outer membrane [LiteratureReference:1252295] Transport of the ADP/ATP carrier of mitochondria from the TOM complex to the TIM22.54 complex [LiteratureReference:1252293] A cooperative action of the ATP-dependent import motor complex and the inner membrane potential drives mitochondrial preprotein import [LiteratureReference:1252278] Tom20 and Tom22 share the common signal recognition pathway in mitochondrial protein import
maxDepth	2
modified	[InstanceEdit:2457655] May, B, 2012-08-27
name	Cargo of TOM40 Proteins Imported by TOM40:TOM70 Complex
schemaClass	DefinedSet
species	[Species:68322] Saccharomyces cerevisiae
stId	R-SCE-1252224
updateTrackers	[UpdateTracker:9873276] Update Tracker - [DefinedSet:1252224] Cargo of TOM40 [cytosol] - v42:[add_removeHasMember]

Referrals

(updatedInstance)	[UpdateTracker:9873276] Update Tracker - [DefinedSet:1252224] Cargo of TOM40 [cytosol] - v42:[add_removeHasMember]
(input)	[Reaction:R-SCE-1252255] TOM40:TOM70 complex translocates proteins from the cytosol to the mitochondrial intermembrane space

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