Reactome | Hydrolysis of phosphatidylcholine

Schema > Reaction > Entries

Hydrolysis of phosphatidylcholine Show undefined attributes

catalystActivity	[CatalystActivity:10906019] calcium-dependent phospholipase A2 activity of Active PLA2:phosphatidylcholine [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:12045] endoplasmic reticulum membrane [Compartment:70101] cytosol [Compartment:17957] endoplasmic reticulum lumen
created	[InstanceEdit:10901498] Wright, Adam, 2024-03-08
dbId	10906021
displayName	Hydrolysis of phosphatidylcholine
eventOf	[Pathway:R-SCE-2142753] Arachidonic acid metabolism - Saccharomyces cerevisiae [Pathway:R-SCE-111995] phospho-PLA2 pathway - Saccharomyces cerevisiae
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-111883] Hydrolysis of phosphatidylcholine - Homo sapiens
input	[SimpleEntity:R-ALL-29356] H2O [cytosol] [SimpleEntity:R-ALL-426925] PC [endoplasmic reticulum membrane]
isInDisease	false
isInferred	true
name	Hydrolysis of phosphatidylcholine
output	[SimpleEntity:R-ALL-140356] AA [endoplasmic reticulum lumen] [SimpleEntity:R-ALL-428981] LPC [endoplasmic reticulum membrane]
precedingEvent	[Reaction:R-SCE-111881] Phospho-cPLA2 translocates to membranes when intracellular calcium levels increase - Saccharomyces cerevisiae
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:68322] Saccharomyces cerevisiae
stId	R-SCE-111883
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SCE-2142753] Arachidonic acid metabolism [Pathway:R-SCE-111995] phospho-PLA2 pathway
(inferredTo)	[Reaction:R-HSA-111883] Hydrolysis of phosphatidylcholine