Reactome | CPA complex components dissociate from polyadenylated pre-mRNA (distal 3'UTR PAS)

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CPA complex components dissociate from polyadenylated pre-mRNA (distal 3'UTR PAS) Show undefined attributes

category	omitted
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10221864
displayName	CPA complex components dissociate from polyadenylated pre-mRNA (distal 3'UTR PAS)
eventOf	[Pathway:R-RNO-9770562] mRNA Polyadenylation - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[BlackBoxEvent:R-HSA-9970428] CPA complex components dissociate from polyadenylated pre-mRNA (distal 3'UTR PAS) - Homo sapiens
input	[Complex:R-RNO-9970319] Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at distal 3'UTR PAS) [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	CPA complex components dissociate from polyadenylated pre-mRNA (distal 3'UTR PAS)
output	[Complex:R-RNO-9970246] CF II:ATP [nucleoplasm] [EntityWithAccessionedSequence:R-RNO-72008] Pabpn1 [nucleoplasm] [DefinedSet:R-RNO-9970174] PAPOLA, PAPOLG, TUT1 [nucleoplasm] [Complex:R-RNO-9970180] PP1:PPP1R10 [nucleoplasm] [EntityWithAccessionedSequence:R-RNO-9970176] Rbbp6 [nucleoplasm] [Complex:R-RNO-9970412] Spliceosomal A complex (capped, methylated, polyadenylated pre-mRNA) [nucleoplasm] [Complex:R-RNO-9970267] Ub-K63-Core CPA complex [nucleoplasm]
precedingEvent	[BlackBoxEvent:R-RNO-9970189] PABPN1-stimulated PAPOL synthesizes polyA tail at distal 3'UTR PAS - Rattus norvegicus
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:48895] Rattus norvegicus
stId	R-RNO-9970428
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-9770562] mRNA Polyadenylation
(inferredTo)	[BlackBoxEvent:R-HSA-9970428] CPA complex components dissociate from polyadenylated pre-mRNA (distal 3'UTR PAS)

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