Reactome | RCHY1 binds alanine-tailed nascent peptide and Ub:UBE2D2

Schema > BlackBoxEvent > Entries

RCHY1 binds alanine-tailed nascent peptide and Ub:UBE2D2 Show undefined attributes

category	omitted
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10221535
displayName	RCHY1 binds alanine-tailed nascent peptide and Ub:UBE2D2
eventOf	[Pathway:R-RNO-9954709] Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-RNO-9954737] RCHY1 K48 polyubiquitinates alanine-tailed nascent peptide - Rattus norvegicus
inferredFrom	[BlackBoxEvent:R-HSA-9954727] RCHY1 binds alanine-tailed nascent peptide and Ub:UBE2D2 - Homo sapiens
input	[Complex:R-RNO-9948304] NEMF:60S ribosomal subunit:peptidyl-tRNA with nascent peptide-Ala [cytosol] [EntityWithAccessionedSequence:R-RNO-976013] RCHY1 [cytosol] [Complex:R-RNO-8939330] Ub:UBE2D2 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	RCHY1 binds alanine-tailed nascent peptide and Ub:UBE2D2
output	[Complex:R-RNO-9954702] RCHY1:Ub:UBE2D2:nascent peptide-Ala [cytosol]
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:48895] Rattus norvegicus
stId	R-RNO-9954727
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-9954709] Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide
(precedingEvent)	[Reaction:R-RNO-9954737] RCHY1 K48 polyubiquitinates alanine-tailed nascent peptide
(inferredTo)	[BlackBoxEvent:R-HSA-9954727] RCHY1 binds alanine-tailed nascent peptide and Ub:UBE2D2

Cite Us!