Reactome | phospho-Cdc25a [nucleoplasm]

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phospho-Cdc25a [nucleoplasm] Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
consumedByEvent	[BlackBoxEvent:R-RNO-69600] Proteolytic degradation of ubiquitinated-Cdc25A - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10103905
displayName	phospho-Cdc25a [nucleoplasm]
endCoordinate	524
hasModifiedResidue	[ModifiedResidue:10103882] O-phospho-L-serine at 76 (in Homo sapiens) [ModifiedResidue:10103883] O-phospho-L-serine at 79 (in Homo sapiens) [ModifiedResidue:10103884] O-phospho-L-serine at 82 (in Homo sapiens) [ModifiedResidue:10103885] O-phospho-L-serine at 88 (in Homo sapiens) [ModifiedResidue:10103886] O-phospho-L-serine at 124 (in Homo sapiens) [ModifiedResidue:10103887] O-phospho-L-serine at 178 (in Homo sapiens) [ModifiedResidue:10103888] O-phospho-L-serine at 279 (in Homo sapiens) [ModifiedResidue:10103889] O-phospho-L-serine at 293 (in Homo sapiens) [GroupModifiedResidue:10103903] ubiquitinylated lysine (polyubiquitin chain [nucleoplasm]) at unknown position
inDisease	false
inferredFrom	[DefinedSet:R-HSA-9943733] PolyUb-p-S82-CDC25A [nucleoplasm] - Homo sapiens [CandidateSet:R-HSA-9944030] PolyUb-p-S76,S79,S82,S88-CDC25A [nucleoplasm] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9944027] PolyUb-p-S76,S79,S82,S88,S124,S178,S279,S293-CDC25A [nucleoplasm] - Homo sapiens
maxDepth	1
name	phospho-Cdc25a PolyUb-p-S76,S79,S82,S88,S124,S178,S279,S293-CDC25A P48965
producedByEvent	[Reaction:R-RNO-69598] Ubiquitination of phosphorylated CDC25A - Rattus norvegicus
referenceEntity	[ReferenceGeneProduct:uniprot:P48965] UniProt:P48965
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48895] Rattus norvegicus
stId	R-RNO-9944027
startCoordinate	1

Referrals

(input)	[BlackBoxEvent:R-RNO-69600] Proteolytic degradation of ubiquitinated-Cdc25A
(output)	[Reaction:R-RNO-69598] Ubiquitination of phosphorylated CDC25A
(inferredTo)	[DefinedSet:R-HSA-9943733] PolyUb-p-S82-CDC25A [nucleoplasm] [CandidateSet:R-HSA-9944030] PolyUb-p-S76,S79,S82,S88-CDC25A [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-9944027] PolyUb-p-S76,S79,S82,S88,S124,S178,S279,S293-CDC25A [nucleoplasm]

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