Reactome | MHC HC:B2M:Erp57 [lumenal side of endoplasmic reticulum membrane]

Schema > Complex > Entries

compartment	[Compartment:5263265] lumenal side of endoplasmic reticulum membrane
componentOf	[Complex:R-RNO-983121] MHC:B2M peptide loading complex [endoplasmic reticulum membrane] - Rattus norvegicus
consumedByEvent	[Reaction:R-RNO-983142] Formation of peptide loading complex (PLC) - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10149459
displayName	MHC HC:B2M:Erp57 [lumenal side of endoplasmic reticulum membrane]
hasComponent	[EntityWithAccessionedSequence:R-RNO-983063] B2m [endoplasmic reticulum lumen] [Complex:R-RNO-983120] monoglucosylated MHC class I HC [lumenal side of endoplasmic reticulum membrane] [EntityWithAccessionedSequence:R-RNO-901028] Pdia3 [endoplasmic reticulum lumen]
inDisease	false
inferredFrom	[Complex:R-HSA-983136] MHC HC:B2M:Erp57 [lumenal side of endoplasmic reticulum membrane] - Homo sapiens
maxDepth	5
name	MHC HC:B2M:Erp57
producedByEvent	[Reaction:R-RNO-983146] Interaction of beta-2-microglobulin (B2M) chain with class I HC - Rattus norvegicus
schemaClass	Complex
species	[Species:48895] Rattus norvegicus
stId	R-RNO-983136
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-RNO-983142] Formation of peptide loading complex (PLC)
(output)	[Reaction:R-RNO-983146] Interaction of beta-2-microglobulin (B2M) chain with class I HC
(hasComponent)	[Complex:R-RNO-983121] MHC:B2M peptide loading complex [endoplasmic reticulum membrane]
(inferredTo)	[Complex:R-HSA-983136] MHC HC:B2M:Erp57 [lumenal side of endoplasmic reticulum membrane]

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