Reactome | CFI:CD46, CR1:C4b, C3b complexes [plasma membrane]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10148175] serine-type endopeptidase activity of CFI:CD46, CR1:C4b, C3b complexes [plasma membrane]
compartment	[Compartment:876] plasma membrane
consumedByEvent	[Reaction:R-RNO-977615] Factor I inactivates MCP/CR1-bound C4b/C3b - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10148140
displayName	CFI:CD46, CR1:C4b, C3b complexes [plasma membrane]
hasComponent	[DefinedSet:R-RNO-981661] CD46, CR1:C4b:C3b complexes [plasma membrane] [Complex:R-RNO-976749] CFI [extracellular region]
inDisease	false
inferredFrom	[Complex:R-HSA-977599] CFI:CD46, CR1:C4b, C3b complexes [plasma membrane] - Homo sapiens
maxDepth	8
name	CFI:CD46, CR1:C4b, C3b complexes
producedByEvent	[Reaction:R-RNO-977602] Complement factor I binds to MCP, CR1:C4b, C3b - Rattus norvegicus
schemaClass	Complex
species	[Species:48895] Rattus norvegicus
stId	R-RNO-977599
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-RNO-977615] Factor I inactivates MCP/CR1-bound C4b/C3b
(physicalEntity)	[CatalystActivity:10148175] serine-type endopeptidase activity of CFI:CD46, CR1:C4b, C3b complexes [plasma membrane]
(output)	[Reaction:R-RNO-977602] Complement factor I binds to MCP, CR1:C4b, C3b
(inferredTo)	[Complex:R-HSA-977599] CFI:CD46, CR1:C4b, C3b complexes [plasma membrane]

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