Reactome | Termination of O-glycan biosynthesis

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Termination of O-glycan biosynthesis Show undefined attributes

created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10224075
displayName	Termination of O-glycan biosynthesis
eventOf	[Pathway:R-RNO-913709] O-linked glycosylation of mucins - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:24451] protein O-linked glycosylation via N-acetyl-galactosamine
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-RNO-977071] ST6GAL1 transfers sialic acid to Tn antigens to form sTn antigens - Rattus norvegicus [Reaction:R-RNO-981814] ST6GALNAC2 transfers sialic acid to Core 1 mucins - Rattus norvegicus [Reaction:R-RNO-981497] ST3GAL1-4 transfers sialic acid to the T antigen at the alpha 3 position - Rattus norvegicus [Reaction:R-RNO-981809] ST6GALNAC3/4 transfers sialic acid to the sialyl T antigen to form the disialyl T antigen - Rattus norvegicus
inferredFrom	[Pathway:R-HSA-977068] Termination of O-glycan biosynthesis - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Termination of O-glycan biosynthesis
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48895] Rattus norvegicus
stId	R-RNO-977068
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-913709] O-linked glycosylation of mucins
(inferredTo)	[Pathway:R-HSA-977068] Termination of O-glycan biosynthesis

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