Reactome | ST3GAL1-4 transfers sialic acid to the T antigen at the alpha 3 position

Schema > Reaction > Entries

ST3GAL1-4 transfers sialic acid to the T antigen at the alpha 3 position Show undefined attributes

catalystActivity	[CatalystActivity:10025054] beta-galactoside (CMP) alpha-2,3-sialyltransferase activity of ST3GAL1-4 [Golgi membrane]
category	transition
compartment	[Compartment:20699] Golgi membrane [Compartment:17963] Golgi lumen
created	[InstanceEdit:9979708] Wright, Adam, 2024-03-07
dbId	10025056
displayName	ST3GAL1-4 transfers sialic acid to the T antigen at the alpha 3 position
eventOf	[Pathway:R-RNO-977068] Termination of O-glycan biosynthesis - Rattus norvegicus
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
followingEvent	[Reaction:R-RNO-981809] ST6GALNAC3/4 transfers sialic acid to the sialyl T antigen to form the disialyl T antigen - Rattus norvegicus
inferredFrom	[Reaction:R-HSA-981497] ST3GAL1-4 transfers sialic acid to the T antigen at the alpha 3 position - Homo sapiens
input	[SimpleEntity:R-ALL-727815] CMP-Neu5Ac [Golgi lumen] [DefinedSet:R-RNO-1462240] Core 1 mucins [Golgi lumen]
isInDisease	false
isInferred	true
name	ST3GAL1-4 transfers sialic acid to the T antigen at the alpha 3 position
output	[SimpleEntity:R-ALL-727810] CMP [Golgi lumen] [DefinedSet:R-RNO-1463569] Sialyl-2,3 T antigens [Golgi lumen]
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-981497
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-977068] Termination of O-glycan biosynthesis
(precedingEvent)	[Reaction:R-RNO-981809] ST6GALNAC3/4 transfers sialic acid to the sialyl T antigen to form the disialyl T antigen
(inferredTo)	[Reaction:R-HSA-981497] ST3GAL1-4 transfers sialic acid to the T antigen at the alpha 3 position

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