Reactome | GABRR pentamers:GABA transports extracellular Cl- to cytosol

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GABRR pentamers:GABA transports extracellular Cl- to cytosol Show undefined attributes

catalystActivity	[CatalystActivity:10147763] chloride channel activity of GABRR pentamers:GABA [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol [Compartment:984] extracellular region
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10147765
displayName	GABRR pentamers:GABA transports extracellular Cl- to cytosol
eventOf	[Pathway:R-RNO-977443] GABA receptor activation - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-975449] GABRR pentamers:GABA transports extracellular Cl- to cytosol - Homo sapiens
input	[SimpleEntity:R-ALL-188972] Cl- [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	GABRR pentamers:GABA transports extracellular Cl- to cytosol
output	[SimpleEntity:R-ALL-352022] Cl- [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-975449
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-977443] GABA receptor activation
(inferredTo)	[Reaction:R-HSA-975449] GABRR pentamers:GABA transports extracellular Cl- to cytosol

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