Reactome | VEGFA-165 dimer binds VEGFA inhibitors

Schema > Reaction > Entries

category	binding
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:9979708] Wright, Adam, 2024-03-07
dbId	10090355
displayName	VEGFA-165 dimer binds VEGFA inhibitors
eventOf	[Pathway:R-RNO-4420097] VEGFA-VEGFR2 Pathway - Rattus norvegicus
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9679477] VEGFA-165 dimer binds VEGFA inhibitors - Homo sapiens
input	[CandidateSet:R-ALL-9679456] VEGFA inhibitors [extracellular region] [Complex:R-RNO-4420158] VEGFA-165 dimer [extracellular region]
isInDisease	false
isInferred	true
name	VEGFA-165 dimer binds VEGFA inhibitors
output	[Complex:R-RNO-9679453] VEGFA-165 dimer:VEGFA inhibitors [extracellular region]
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-9679477
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-RNO-4420097] VEGFA-VEGFR2 Pathway
(inferredTo)	[Reaction:R-HSA-9679477] VEGFA-165 dimer binds VEGFA inhibitors