Reactome | Rac1:GTP [plasma membrane]

Schema > Complex > Entries

Rac1:GTP [plasma membrane] Show undefined attributes

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-RNO-5663231] RAC1:GTP:FMNL1 [plasma membrane] - Rattus norvegicus [Complex:R-RNO-5218784] p-VAV family:PIP3:RAC1:GTP [plasma membrane] - Rattus norvegicus [Complex:R-RNO-2029148] p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] - Rattus norvegicus [Complex:R-RNO-2685706] p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP [plasma membrane] - Rattus norvegicus
consumedByEvent	[BlackBoxEvent:R-RNO-9691168] RAC1 translocates to the endoplasmic reticulum membrane - Rattus norvegicus [Reaction:R-RNO-445072] Interaction of PAK1 with Rac1-GTP - Rattus norvegicus [Reaction:R-RNO-9013145] RAC1 binds effectors at the plasma membrane - Rattus norvegicus [Reaction:R-RNO-9013144] RAC1 GAPs stimulate RAC1 GTPase activity - Rattus norvegicus [Reaction:R-RNO-400682] Active Rac1 interacts with Plexin-B1:Sema4D - Rattus norvegicus [Reaction:R-RNO-5218827] NADPH oxidase 2 (NOX2) complex binds RAC1 - Rattus norvegicus [Reaction:R-RNO-5668735] RAC1:GTP binds NOX3 complex - Rattus norvegicus [Reaction:R-RNO-5668714] RAC1:GTP binds NOX1 complex - Rattus norvegicus [Reaction:R-RNO-2029465] RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) - Rattus norvegicus
created	[InstanceEdit:9628561] Orlic-Milacic, Marija, 2018-11-09
dbId	9628560
deleted	[Deleted:9628563] Deletion of instance: 9619809
displayName	Rac1:GTP [plasma membrane]
hasComponent	[SimpleEntity:R-ALL-29438] GTP [cytosol] [EntityWithAccessionedSequence:R-RNO-205143] Rac1 [plasma membrane]
inDisease	false
includedLocation	[Compartment:70101] cytosol
inferredFrom	[Complex:R-HSA-442641] RAC1:GTP [plasma membrane] - Homo sapiens
isChimeric	false
maxDepth	2
memberOf	[DefinedSet:R-RNO-9615275] RAC1:GTP,RAC2:GTP,RHOG:GTP [plasma membrane] - Rattus norvegicus [DefinedSet:R-RNO-389778] CDC42:GTP, RAC1:GTP [plasma membrane] - Rattus norvegicus [DefinedSet:R-RNO-8981458] RHOA,RHOB,RHOC,RAC1:GTP [plasma membrane] - Rattus norvegicus
modified	[InstanceEdit:9628564] Orlic-Milacic, Marija, 2018-11-09
name	Rac1:GTP
producedByEvent	[Reaction:R-RNO-389348] Activation of Rac1 by pVav1 - Rattus norvegicus [Reaction:R-RNO-9619811] p-S516-Arhgef7 activates Rac1 - Rattus norvegicus [BlackBoxEvent:R-RNO-9032798] DOCK3 activates RAC1 - Rattus norvegicus [Reaction:R-RNO-1433415] Activation of RAC1 - Rattus norvegicus [BlackBoxEvent:R-RNO-8875591] DOCK7 activates RAC1 - Rattus norvegicus [Reaction:R-RNO-9013143] RAC1 GEFs activate RAC1 - Rattus norvegicus [Reaction:R-RNO-8848618] Activation of RAC1 by the PXN:CRK complex - Rattus norvegicus [Reaction:R-RNO-5218839] DOCK180:ELMO exchanges GTP for GDP, activating RAC1 - Rattus norvegicus [Reaction:R-RNO-2029451] Activation of RAC1 by VAV - Rattus norvegicus [Reaction:R-RNO-2029467] Activation of RAC1 by CRKII:DOCK180:ELMO - Rattus norvegicus [Reaction:R-RNO-2424476] Activation of RAC1 by VAV2/3 - Rattus norvegicus [Reaction:R-RNO-445064] Activation of Rac1 by VAV2 - Rattus norvegicus [Reaction:R-RNO-3928642] TIAM1 exchanges GTP for GDP on RAC1, activating it - Rattus norvegicus [Reaction:R-RNO-3928628] VAV exchanges GTP for GDP on RAC1, activating it - Rattus norvegicus [Reaction:R-RNO-4093336] p-TIAM1 exchanges GTP for GDP on RAC1, activating it - Rattus norvegicus
schemaClass	Complex
species	[Species:48895] Rattus norvegicus
stId	R-RNO-9628560

Referrals

(hasComponent)	[Complex:R-RNO-2685706] p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP [plasma membrane] [Complex:R-RNO-2029148] p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] [Complex:R-RNO-2130182] p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] [Complex:R-RNO-2029147] WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] [Complex:R-RNO-5218784] p-VAV family:PIP3:RAC1:GTP [plasma membrane] [Complex:R-RNO-399872] Sema3A:Nrp-1:pPlexinA:Fyn:Fes:Rac-1-GTP [plasma membrane] [Complex:R-RNO-418826] NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:RAC1:GTP [plasma membrane] [Complex:R-RNO-5663231] RAC1:GTP:FMNL1 [plasma membrane] [Complex:R-RNO-400679] Sema4D:pPlexin-B1:Met:RAC1-GTP [plasma membrane] [Complex:R-RNO-5218774] NOX2 complex:RAC1:GTP [plasma membrane] [Complex:R-RNO-5668738] NOX3 complex:RAC1:GTP [plasma membrane] [Complex:R-RNO-5668712] NOX1 complex:RAC1:GTP [plasma membrane] [Complex:R-RNO-445001] pPAK1:Rac1-GTP [cytosol] [Complex:R-RNO-9013182] RAC1:GTP:RAC1 effectors [plasma membrane]
(input)	[BlackBoxEvent:R-RNO-9691168] RAC1 translocates to the endoplasmic reticulum membrane [Reaction:R-RNO-2029465] RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) [Reaction:R-RNO-400682] Active Rac1 interacts with Plexin-B1:Sema4D [Reaction:R-RNO-5218827] NADPH oxidase 2 (NOX2) complex binds RAC1 [Reaction:R-RNO-5668735] RAC1:GTP binds NOX3 complex [Reaction:R-RNO-5668714] RAC1:GTP binds NOX1 complex [Reaction:R-RNO-445072] Interaction of PAK1 with Rac1-GTP [Reaction:R-RNO-9013145] RAC1 binds effectors at the plasma membrane [Reaction:R-RNO-9013144] RAC1 GAPs stimulate RAC1 GTPase activity
(output)	[Reaction:R-RNO-8848618] Activation of RAC1 by the PXN:CRK complex [Reaction:R-RNO-5218839] DOCK180:ELMO exchanges GTP for GDP, activating RAC1 [Reaction:R-RNO-2029451] Activation of RAC1 by VAV [Reaction:R-RNO-2029467] Activation of RAC1 by CRKII:DOCK180:ELMO [Reaction:R-RNO-389348] Activation of Rac1 by pVav1 [Reaction:R-RNO-9619811] p-S516-Arhgef7 activates Rac1 [BlackBoxEvent:R-RNO-9032798] DOCK3 activates RAC1 [Reaction:R-RNO-2424476] Activation of RAC1 by VAV2/3 [Reaction:R-RNO-1433415] Activation of RAC1 [BlackBoxEvent:R-RNO-8875591] DOCK7 activates RAC1 [Reaction:R-RNO-445064] Activation of Rac1 by VAV2 [Reaction:R-RNO-3928642] TIAM1 exchanges GTP for GDP on RAC1, activating it [Reaction:R-RNO-3928628] VAV exchanges GTP for GDP on RAC1, activating it [Reaction:R-RNO-4093336] p-TIAM1 exchanges GTP for GDP on RAC1, activating it [Reaction:R-RNO-9013143] RAC1 GEFs activate RAC1
(inferredTo)	[Complex:R-HSA-442641] RAC1:GTP [plasma membrane]
(hasMember)	[DefinedSet:R-RNO-9615275] RAC1:GTP,RAC2:GTP,RHOG:GTP [plasma membrane] [CandidateSet:R-RNO-9959034] RAC1:GTP,(CDC42:GTP) [plasma membrane] [DefinedSet:R-RNO-389778] CDC42:GTP, RAC1:GTP [plasma membrane] [DefinedSet:R-RNO-8981458] RHOA,RHOB,RHOC,RAC1:GTP [plasma membrane]
(activeUnit)	[CatalystActivity:10181618] GTPase activity of SRGAP2:RAC1:GTP:FMNL1:Profilin:G-actin [plasma membrane]
(replacementInstances)	[Deleted:9628563] Deletion of instance: 9619809

Cite Us!