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Go!
Schema
>
Complex
>
Entries
Rac1:GTP [plasma membrane]
Show undefined attributes
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compartment
[Compartment:876] plasma membrane
componentOf
[Complex:R-RNO-9013182] RAC1:GTP:RAC1 effectors [plasma membrane] - Rattus norvegicus
[Complex:R-RNO-5668712] NOX1 complex:RAC1:GTP [plasma membrane] - Rattus norvegicus
[Complex:R-RNO-2029148] p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] - Rattus norvegicus
[Complex:R-RNO-2029147] WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] - Rattus norvegicus
consumedByEvent
[BlackBoxEvent:R-RNO-9691168] RAC1 translocates to the endoplasmic reticulum membrane - Rattus norvegicus
[Reaction:R-RNO-9013144] RAC1 GAPs stimulate RAC1 GTPase activity - Rattus norvegicus
[Reaction:R-RNO-9013145] RAC1 binds effectors at the plasma membrane - Rattus norvegicus
[Reaction:R-RNO-445072] Interaction of PAK1 with Rac1-GTP - Rattus norvegicus
[Reaction:R-RNO-5668714] RAC1:GTP binds NOX1 complex - Rattus norvegicus
[Reaction:R-RNO-5668735] RAC1:GTP binds NOX3 complex - Rattus norvegicus
[Reaction:R-RNO-5218827] NADPH oxidase 2 (NOX2) complex binds RAC1 - Rattus norvegicus
[Reaction:R-RNO-400682] Active Rac1 interacts with Plexin-B1:Sema4D - Rattus norvegicus
[Reaction:R-RNO-2029465] RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) - Rattus norvegicus
created
[InstanceEdit:9628561] Orlic-Milacic, Marija, 2018-11-09
dbId
9628560
displayName
Rac1:GTP [plasma membrane]
hasComponent
[SimpleEntity:R-ALL-29438] GTP [cytosol]
[EntityWithAccessionedSequence:R-RNO-205143] Rac1 [plasma membrane]
inDisease
false
includedLocation
[Compartment:70101] cytosol
inferredFrom
[Complex:R-HSA-442641] RAC1:GTP [plasma membrane] - Homo sapiens
isChimeric
false
memberOf
[DefinedSet:R-RNO-9615275] RAC1:GTP,RAC2:GTP,RHOG:GTP [plasma membrane] - Rattus norvegicus
[DefinedSet:R-RNO-389778] CDC42:GTP, RAC1:GTP [plasma membrane] - Rattus norvegicus
[DefinedSet:R-RNO-8981458] RHOA,RHOB,RHOC,RAC1:GTP [plasma membrane] - Rattus norvegicus
modified
[InstanceEdit:9628564] Orlic-Milacic, Marija, 2018-11-09
name
Rac1:GTP
producedByEvent
[Reaction:R-RNO-9013143] RAC1 GEFs activate RAC1 - Rattus norvegicus
[BlackBoxEvent:R-RNO-9032798] DOCK3 activates RAC1 - Rattus norvegicus
[BlackBoxEvent:R-RNO-8875591] DOCK7 activates RAC1 - Rattus norvegicus
[Reaction:R-RNO-1433415] Activation of RAC1 - Rattus norvegicus
[Reaction:R-RNO-9619811] p-S516-Arhgef7 activates Rac1 - Rattus norvegicus
[Reaction:R-RNO-389348] Activation of Rac1 by pVav1 - Rattus norvegicus
[Reaction:R-RNO-4093336] p-TIAM1 exchanges GTP for GDP on RAC1, activating it - Rattus norvegicus
[Reaction:R-RNO-3928628] VAV exchanges GTP for GDP on RAC1, activating it - Rattus norvegicus
[Reaction:R-RNO-3928642] TIAM1 exchanges GTP for GDP on RAC1, activating it - Rattus norvegicus
[Reaction:R-RNO-445064] Activation of Rac1 by VAV2 - Rattus norvegicus
[Reaction:R-RNO-2424476] Activation of RAC1 by VAV2/3 - Rattus norvegicus
[Reaction:R-RNO-2029451] Activation of RAC1 by VAV - Rattus norvegicus
[Reaction:R-RNO-2029467] Activation of RAC1 by CRKII:DOCK180:ELMO - Rattus norvegicus
[Reaction:R-RNO-5218839] DOCK180:ELMO exchanges GTP for GDP, activating RAC1 - Rattus norvegicus
[Reaction:R-RNO-8848618] Activation of RAC1 by the PXN:CRK complex - Rattus norvegicus
schemaClass
Complex
species
[Species:48895] Rattus norvegicus
stId
R-RNO-9628560
Referrals
(input)
[BlackBoxEvent:R-RNO-9691168] RAC1 translocates to the endoplasmic reticulum membrane
[Reaction:R-RNO-9013144] RAC1 GAPs stimulate RAC1 GTPase activity
[Reaction:R-RNO-9013145] RAC1 binds effectors at the plasma membrane
[Reaction:R-RNO-445072] Interaction of PAK1 with Rac1-GTP
[Reaction:R-RNO-5668714] RAC1:GTP binds NOX1 complex
[Reaction:R-RNO-5668735] RAC1:GTP binds NOX3 complex
[Reaction:R-RNO-5218827] NADPH oxidase 2 (NOX2) complex binds RAC1
[Reaction:R-RNO-400682] Active Rac1 interacts with Plexin-B1:Sema4D
[Reaction:R-RNO-2029465] RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC)
(output)
[Reaction:R-RNO-9013143] RAC1 GEFs activate RAC1
[Reaction:R-RNO-4093336] p-TIAM1 exchanges GTP for GDP on RAC1, activating it
[Reaction:R-RNO-3928628] VAV exchanges GTP for GDP on RAC1, activating it
[Reaction:R-RNO-3928642] TIAM1 exchanges GTP for GDP on RAC1, activating it
[Reaction:R-RNO-445064] Activation of Rac1 by VAV2
[BlackBoxEvent:R-RNO-9032798] DOCK3 activates RAC1
[BlackBoxEvent:R-RNO-8875591] DOCK7 activates RAC1
[Reaction:R-RNO-1433415] Activation of RAC1
[Reaction:R-RNO-9619811] p-S516-Arhgef7 activates Rac1
[Reaction:R-RNO-2424476] Activation of RAC1 by VAV2/3
[Reaction:R-RNO-2029451] Activation of RAC1 by VAV
[Reaction:R-RNO-2029467] Activation of RAC1 by CRKII:DOCK180:ELMO
[Reaction:R-RNO-5218839] DOCK180:ELMO exchanges GTP for GDP, activating RAC1
[Reaction:R-RNO-389348] Activation of Rac1 by pVav1
[Reaction:R-RNO-8848618] Activation of RAC1 by the PXN:CRK complex
(hasComponent)
[Complex:R-RNO-9013182] RAC1:GTP:RAC1 effectors [plasma membrane]
[Complex:R-RNO-445001] pPAK1:Rac1-GTP [cytosol]
[Complex:R-RNO-5668712] NOX1 complex:RAC1:GTP [plasma membrane]
[Complex:R-RNO-5668738] NOX3 complex:RAC1:GTP [plasma membrane]
[Complex:R-RNO-5218774] NOX2 complex:RAC1:GTP [plasma membrane]
[Complex:R-RNO-400679] Sema4D:pPlexin-B1:Met:RAC1-GTP [plasma membrane]
[Complex:R-RNO-399872] Sema3A:Nrp-1:pPlexinA:Fyn:Fes:Rac-1-GTP [plasma membrane]
[Complex:R-RNO-5218784] p-VAV family:PIP3:RAC1:GTP [plasma membrane]
[Complex:R-RNO-2029147] WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane]
[Complex:R-RNO-2029148] p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol]
[Complex:R-RNO-2130182] p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane]
[Complex:R-RNO-418826] NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:RAC1:GTP [plasma membrane]
[Complex:R-RNO-5663231] RAC1:GTP:FMNL1 [plasma membrane]
[Complex:R-RNO-2685706] p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP [plasma membrane]
(hasMember)
[DefinedSet:R-RNO-8981458] RHOA,RHOB,RHOC,RAC1:GTP [plasma membrane]
[DefinedSet:R-RNO-389778] CDC42:GTP, RAC1:GTP [plasma membrane]
[DefinedSet:R-RNO-9615275] RAC1:GTP,RAC2:GTP,RHOG:GTP [plasma membrane]
(activeUnit)
[CatalystActivity:10059031] GTPase activity of SRGAP2:RAC1:GTP:FMNL1:Profilin:G-actin [plasma membrane]
(inferredTo)
[Complex:R-HSA-442641] RAC1:GTP [plasma membrane]
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