Reactome | Egr2 and Sox10 bind the Mag gene

Schema > Reaction > Entries

authored	[InstanceEdit:9616129] Rothfels, Karen, 2018-08-09
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9616120] Rothfels, Karen, 2018-08-09
dbId	9616122
displayName	Egr2 and Sox10 bind the Mag gene
edited	[InstanceEdit:9676974] Rothfels, Karen, 2020-02-24
input	[EntityWithAccessionedSequence:R-RNO-9614791] Egr2 [nucleoplasm] [EntityWithAccessionedSequence:R-RNO-9616121] Mag gene [nucleoplasm] 2 × [EntityWithAccessionedSequence:R-RNO-9614292] Sox10 [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9615605] Interactions of Sox10 and Egr2 in myelin gene regulation [LiteratureReference:9615601] In vivo detection of Egr2 binding to target genes during peripheral nerve myelination [LiteratureReference:9613730] Neuropathy-associated Egr2 mutants disrupt cooperative activation of myelin protein zero by Egr2 and Sox10
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Egr2 and Sox10 bind the Mag gene
orthologousEvent	[BlackBoxEvent:R-HSA-9614778] MAG gene expression - Homo sapiens
output	[Complex:R-RNO-9616119] Mag gene:Egr2:Sox10 [nucleoplasm]
releaseDate	2020-03-17
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9674653] Aletta, John M, 2020-01-17
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-9616122
summation	[Summation:9616086] By ChIP analysis, Egr2 and Sox10 bind to their cognate sites...

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