Reactome | Binding of AP1 transcriptional activator complexes to CCND1 promoter

Schema > Reaction > Entries

Binding of AP1 transcriptional activator complexes to CCND1 promoter Show undefined attributes

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10208433
displayName	Binding of AP1 transcriptional activator complexes to CCND1 promoter
eventOf	[Pathway:R-RNO-9018519] Estrogen-dependent gene expression - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9009371] Binding of AP1 transcriptional activator complexes to CCND1 promoter - Homo sapiens
input	[Complex:R-RNO-9009057] CCND1 gene:H3K4me2 nucleosome:FOXA1:GATA3 [nucleoplasm] [EntityWithAccessionedSequence:R-RNO-381325] Ep300 [nucleoplasm] [Complex:R-RNO-9009370] ESTG:ESR1 dimer:ATF2:JUN [nucleoplasm] [Complex:R-RNO-9009373] ESTG:ESR1 dimer:JUN:FOS [nucleoplasm] [EntityWithAccessionedSequence:R-RNO-83836] Pou2f1 [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	Binding of AP1 transcriptional activator complexes to CCND1 promoter
output	[Complex:R-RNO-9009369] CCND1 gene:H3K4me2 nucleosome:FOXA1:GATA3:ESTG:ESR1 dimer:JUN:ATF2:POUF21:ESTG:ESR1 dimer:JUN:FOS [nucleoplasm]
precedingEvent	[Reaction:R-RNO-9009065] FOXA1 and GATA3 bind to CCND1 promoter - Rattus norvegicus [Reaction:R-RNO-8939201] ESR dimerizes - Rattus norvegicus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-9009371
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-9018519] Estrogen-dependent gene expression
(inferredTo)	[Reaction:R-HSA-9009371] Binding of AP1 transcriptional activator complexes to CCND1 promoter

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