Reactome | Signaling by NTRK2 (TRKB)

Schema > Pathway > Entries

created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10225237
displayName	Signaling by NTRK2 (TRKB)
eventOf	[Pathway:R-RNO-166520] Signaling by NTRKs - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:182] neurotrophin TRK receptor signaling pathway
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-RNO-9026527] Activated NTRK2 signals through PLCG1 - Rattus norvegicus [Pathway:R-RNO-9028731] Activated NTRK2 signals through FRS2 and FRS3 - Rattus norvegicus [Pathway:R-RNO-9032500] Activated NTRK2 signals through FYN - Rattus norvegicus
inferredFrom	[Pathway:R-HSA-9006115] Signaling by NTRK2 (TRKB) - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	4
name	Signaling by NTRK2 (TRKB)
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48895] Rattus norvegicus
stId	R-RNO-9006115
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-RNO-166520] Signaling by NTRKs
(inferredTo)	[Pathway:R-HSA-9006115] Signaling by NTRK2 (TRKB)

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