Reactome | phospho-Pten [cytosol]

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phospho-Pten [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10198257
displayName	phospho-Pten [cytosol]
endCoordinate	403
hasModifiedResidue	[ModifiedResidue:10198250] adenosine diphosphoribosyl (ADP-ribosyl) modified residue at 40 (in Homo sapiens) [ModifiedResidue:10198251] adenosine diphosphoribosyl (ADP-ribosyl) modified residue at 150 (in Homo sapiens) [ModifiedResidue:10198252] adenosine diphosphoribosyl (ADP-ribosyl) modified residue at 326 (in Homo sapiens) [GroupModifiedResidue:10198253] ubiquitinylated lysine (polyubiquitin chain [cytosol]) at 342 (in Homo sapiens) [GroupModifiedResidue:10198254] ubiquitinylated lysine (polyubiquitin chain [cytosol]) at 344 (in Homo sapiens) [GroupModifiedResidue:10198255] ubiquitinylated lysine (polyubiquitin chain [cytosol]) at 349 (in Homo sapiens)
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-8948841] PolyUb-K324,K344,K349-RibC-E40,E150,D326-PTEN [cytosol] - Homo sapiens
maxDepth	1
memberOf	[DefinedSet:R-RNO-8948842] PolyUb-PTEN, K48polyUb-K289-PTEN, PolyUb-K324,K344,K349-RibC-E40,E150,D326-PTEN [cytosol] - Rattus norvegicus
name	phospho-Pten PolyUb-K324,K344,K349-RibC-E40,E150,D326-PTEN O54857
producedByEvent	[Reaction:R-RNO-8948832] RNF146 polyubiquitinates PARylated PTEN - Rattus norvegicus
referenceEntity	[ReferenceGeneProduct:uniprot:O54857] UniProt:O54857
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48895] Rattus norvegicus
stId	R-RNO-8948841
startCoordinate	2

Referrals

(hasMember)	[DefinedSet:R-RNO-8948842] PolyUb-PTEN, K48polyUb-K289-PTEN, PolyUb-K324,K344,K349-RibC-E40,E150,D326-PTEN [cytosol]
(output)	[Reaction:R-RNO-8948832] RNF146 polyubiquitinates PARylated PTEN
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-8948841] PolyUb-K324,K344,K349-RibC-E40,E150,D326-PTEN [cytosol]

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