Reactome | hp-IRAK1:3xK63polyUb-TRAF6 [cytosol]

Schema > Complex > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-RNO-450185] hp-IRAK1:K6-poly-Ub oligo-TRAF6:TAK1 complex [cytosol] - Rattus norvegicus
consumedByEvent	[Reaction:R-RNO-446870] Polyubiquitinated TRAF6 binds the TAK1 complex - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10140912
displayName	hp-IRAK1:3xK63polyUb-TRAF6 [cytosol]
hasComponent	[Complex:R-RNO-450147] hp-IRAK1:K63polyUb-TRAF6 [cytosol] 2 × [EntityWithAccessionedSequence:R-RNO-2685681] Traf6 [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-8948065] hp-IRAK1:3xK63polyUb-TRAF6 [cytosol] - Homo sapiens
maxDepth	3
name	hp-IRAK1:3xK63polyUb-TRAF6
producedByEvent	[BlackBoxEvent:R-RNO-8948018] UBE2N:UBE2V1 dissociates from hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 - Rattus norvegicus
schemaClass	Complex
species	[Species:48895] Rattus norvegicus
stId	R-RNO-8948065
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-RNO-446870] Polyubiquitinated TRAF6 binds the TAK1 complex
(hasComponent)	[Complex:R-RNO-450185] hp-IRAK1:K6-poly-Ub oligo-TRAF6:TAK1 complex [cytosol]
(output)	[BlackBoxEvent:R-RNO-8948018] UBE2N:UBE2V1 dissociates from hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1
(inferredTo)	[Complex:R-HSA-8948065] hp-IRAK1:3xK63polyUb-TRAF6 [cytosol]

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