Reactome | Polyubiquitinated TRAF6 binds the TAK1 complex

Schema > Reaction > Entries

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10140916
displayName	Polyubiquitinated TRAF6 binds the TAK1 complex
eventOf	[Pathway:R-RNO-9020702] Interleukin-1 signaling - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-446870] Polyubiquitinated TRAF6 binds the TAK1 complex - Homo sapiens
input	[Complex:R-RNO-8948065] hp-IRAK1:3xK63polyUb-TRAF6 [cytosol] [Complex:R-RNO-446878] TAK1 complex [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Polyubiquitinated TRAF6 binds the TAK1 complex
output	[Complex:R-RNO-450185] hp-IRAK1:K6-poly-Ub oligo-TRAF6:TAK1 complex [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-446870
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-RNO-9020702] Interleukin-1 signaling
(inferredTo)	[Reaction:R-HSA-446870] Polyubiquitinated TRAF6 binds the TAK1 complex

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