Reactome | TFAP2 homo- and heterodimers bind CITED and EP300/CREBBP

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TFAP2 homo- and heterodimers bind CITED and EP300/CREBBP Show undefined attributes

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10200398
displayName	TFAP2 homo- and heterodimers bind CITED and EP300/CREBBP
eventOf	[Pathway:R-RNO-8866907] Activation of the TFAP2 (AP-2) family of transcription factors - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-8864307] TFAP2 homo- and heterodimers bind CITED and EP300/CREBBP - Homo sapiens
input	[CandidateSet:R-RNO-8864305] CITED2,CITED4,(CITED1) [nucleoplasm] [EntityWithAccessionedSequence:R-RNO-193545] CREBBP [nucleoplasm] [EntityWithAccessionedSequence:R-RNO-381325] Ep300 [nucleoplasm] [Complex:R-RNO-8864283] TFAP2 homo- and heterodimers [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	TFAP2 homo- and heterodimers bind CITED and EP300/CREBBP
output	[Complex:R-RNO-8864321] TFAP2 homo- and heterodimers:CITED2,CITED4,(CITED1):EP300:CREBBP [nucleoplasm]
precedingEvent	[Reaction:R-RNO-8864278] AP-2 (TFAP2) transcription factors form homo- and heterodimers - Rattus norvegicus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-8864307
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-8866907] Activation of the TFAP2 (AP-2) family of transcription factors
(inferredTo)	[Reaction:R-HSA-8864307] TFAP2 homo- and heterodimers bind CITED and EP300/CREBBP

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