Reactome | FYN phosphorylates DAB1 in RELN:VLDLR:DAB1:SH3KBP1

Schema > Reaction > Entries

FYN phosphorylates DAB1 in RELN:VLDLR:DAB1:SH3KBP1 Show undefined attributes

catalystActivity	[CatalystActivity:10134711] protein tyrosine kinase activity of FYN [cytosol]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10199377
displayName	FYN phosphorylates DAB1 in RELN:VLDLR:DAB1:SH3KBP1
eventOf	[Pathway:R-RNO-8866376] Reelin signalling pathway - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-8855237] FYN phosphorylates DAB1 in RELN:VLDLR:DAB1:SH3KBP1 - Homo sapiens
input	3 × [SimpleEntity:R-ALL-113592] ATP [cytosol] [Complex:R-RNO-8855258] RELN:VLDLR:DAB1:SH3KBP1 [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	FYN phosphorylates DAB1 in RELN:VLDLR:DAB1:SH3KBP1
output	3 × [SimpleEntity:R-ALL-29370] ADP [cytosol] [Complex:R-RNO-8855226] RELN:VLDLR:p-Y198,220,232-DAB1:SH3KBP1 [plasma membrane]
precedingEvent	[Reaction:R-RNO-8855259] RELN:VLDLR:DAB1 binds SH3KBP1 - Rattus norvegicus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-8855237
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-8866376] Reelin signalling pathway
(inferredTo)	[Reaction:R-HSA-8855237] FYN phosphorylates DAB1 in RELN:VLDLR:DAB1:SH3KBP1

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