Reactome | Platelet activation, signaling and aggregation

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Platelet activation, signaling and aggregation Show undefined attributes

created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10222559
displayName	Platelet activation, signaling and aggregation
eventOf	[TopLevelPathway:R-RNO-109582] Hemostasis - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:20684] platelet activation
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-RNO-430116] GP1b-IX-V activation signalling - Rattus norvegicus [Pathway:R-RNO-392518] Signal amplification - Rattus norvegicus [Pathway:R-RNO-456926] Thrombin signalling through proteinase activated receptors (PARs) - Rattus norvegicus [Pathway:R-RNO-114604] GPVI-mediated activation cascade - Rattus norvegicus [Pathway:R-RNO-76009] Platelet Aggregation (Plug Formation) - Rattus norvegicus [Pathway:R-RNO-114508] Effects of PIP2 hydrolysis - Rattus norvegicus [Pathway:R-RNO-76005] Response to elevated platelet cytosolic Ca2+ - Rattus norvegicus
inferredFrom	[Pathway:R-HSA-76002] Platelet activation, signaling and aggregation - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	5
name	Platelet activation, signaling and aggregation
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48895] Rattus norvegicus
stId	R-RNO-76002
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[TopLevelPathway:R-RNO-109582] Hemostasis
(inferredTo)	[Pathway:R-HSA-76002] Platelet activation, signaling and aggregation

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