Reactome | XRCC4:LIG4 [nucleoplasm]

Schema > Complex > Entries

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-RNO-5687362] p-T2609,S2612,T2638,T2647-PRKDC:XRCC5:XRCC6:p-S516,S645-DCLRE1C:XRCC4:LIG4:NHEJ1:POLL,POLM:Extended ligatable DNA DSB ends [nucleoplasm] - Rattus norvegicus [Complex:R-RNO-5693617] p-T2609,S2612,T2638,T2647-PRKDC:XRCC5:XRCC6:p-S516,S645-DCLRE1C:XRCC4:LIG4:NHEJ1:POLL,POLM:Ligatable DNA DSB ends [nucleoplasm] - Rattus norvegicus
consumedByEvent	[Reaction:R-RNO-5693574] XRCC4:LIG4, NHEJ1 and POLL or POLM bind DNA DSBs in NHEJ - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10184431
displayName	XRCC4:LIG4 [nucleoplasm]
hasComponent	[EntityWithAccessionedSequence:R-RNO-53791] Lig4 [nucleoplasm] [Complex:R-RNO-5687210] XRCC4 homodimer [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-75912] XRCC4:LIG4 [nucleoplasm] - Homo sapiens
maxDepth	3
name	XRCC4:LIG4
schemaClass	Complex
species	[Species:48895] Rattus norvegicus
stId	R-RNO-75912
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-RNO-5693574] XRCC4:LIG4, NHEJ1 and POLL or POLM bind DNA DSBs in NHEJ
(hasComponent)	[Complex:R-RNO-5687362] p-T2609,S2612,T2638,T2647-PRKDC:XRCC5:XRCC6:p-S516,S645-DCLRE1C:XRCC4:LIG4:NHEJ1:POLL,POLM:Extended ligatable DNA DSB ends [nucleoplasm] [Complex:R-RNO-5693617] p-T2609,S2612,T2638,T2647-PRKDC:XRCC5:XRCC6:p-S516,S645-DCLRE1C:XRCC4:LIG4:NHEJ1:POLL,POLM:Ligatable DNA DSB ends [nucleoplasm]
(inferredTo)	[Complex:R-HSA-75912] XRCC4:LIG4 [nucleoplasm]