Reactome | Base-Excision Repair, AP Site Formation

Schema > Pathway > Entries

compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10222427
displayName	Base-Excision Repair, AP Site Formation
eventOf	[Pathway:R-RNO-73884] Base Excision Repair - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:17137] base-excision repair, AP site formation
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-RNO-73927] Depurination - Rattus norvegicus [Pathway:R-RNO-73928] Depyrimidination - Rattus norvegicus
inferredFrom	[Pathway:R-HSA-73929] Base-Excision Repair, AP Site Formation - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	4
name	Base-Excision Repair, AP Site Formation
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48895] Rattus norvegicus
stId	R-RNO-73929
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-RNO-73884] Base Excision Repair
(hasEncapsulatedEvent)	[Pathway:R-RNO-73933] Resolution of Abasic Sites (AP sites)
(inferredTo)	[Pathway:R-HSA-73929] Base-Excision Repair, AP Site Formation

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