Reactome | PGK complexes dephosphorylate 1,3BPG

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PGK complexes dephosphorylate 1,3BPG Show undefined attributes

catalystActivity	[CatalystActivity:10104495] phosphoglycerate kinase activity of PGK complexes [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10105832
displayName	PGK complexes dephosphorylate 1,3BPG
eventOf	[Pathway:R-RNO-70171] Glycolysis - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-RNO-71654] PGAM dimers isomerise 3PG to 2PG - Rattus norvegicus
inferredFrom	[Reaction:R-HSA-71850] PGK complexes dephosphorylate 1,3BPG - Homo sapiens
input	[SimpleEntity:R-ALL-29800] 1,3BPG [cytosol] [SimpleEntity:R-ALL-29370] ADP [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	PGK complexes dephosphorylate 1,3BPG 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP 1,3-Bisphosphoglycerate and ADP react to form 3-phosphoglycerate and ATP
output	[SimpleEntity:R-ALL-29728] 3PG [cytosol] [SimpleEntity:R-ALL-113592] ATP [cytosol]
precedingEvent	[Reaction:R-RNO-70449] GADPH tetramer dehydrogenates GA3P - Rattus norvegicus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-71850
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-70171] Glycolysis
(precedingEvent)	[Reaction:R-RNO-71654] PGAM dimers isomerise 3PG to 2PG
(inferredTo)	[Reaction:R-HSA-71850] PGK complexes dephosphorylate 1,3BPG

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