Reactome | G1/S DNA Damage Checkpoints

Schema > Pathway > Entries

created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10221975
displayName	G1/S DNA Damage Checkpoints
eventOf	[Pathway:R-RNO-69620] Cell Cycle Checkpoints - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Pathway:R-RNO-69580] p53-Dependent G1/S DNA damage checkpoint - Rattus norvegicus [Pathway:R-RNO-69613] p53-Independent G1/S DNA Damage Checkpoint - Rattus norvegicus
inferredFrom	[Pathway:R-HSA-69615] G1/S DNA Damage Checkpoints - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	6
name	G1/S DNA Damage Checkpoints
precedingEvent	[Pathway:R-RNO-69236] G1 Phase - Rattus norvegicus
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48895] Rattus norvegicus
stId	R-RNO-69615
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-RNO-69620] Cell Cycle Checkpoints
(inferredTo)	[Pathway:R-HSA-69615] G1/S DNA Damage Checkpoints

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