Reactome | ESRP1 and 2 bind FGFR2 pre-mRNA to promote FGFR2b maturation and expression

Schema > Reaction > Entries

ESRP1 and 2 bind FGFR2 pre-mRNA to promote FGFR2b maturation and expression Show undefined attributes

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10194153
displayName	ESRP1 and 2 bind FGFR2 pre-mRNA to promote FGFR2b maturation and expression
eventOf	[Pathway:R-RNO-6803529] FGFR2 alternative splicing - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-6803527] ESRP1 and 2 bind FGFR2 pre-mRNA to promote FGFR2b maturation and expression - Homo sapiens
input	[Complex:R-RNO-6803524] capped, methylated pre-FGFR2 mRNA:CBC complex [nucleoplasm] [EntityWithAccessionedSequence:R-RNO-6803472] Esrp1 [nucleoplasm] [EntityWithAccessionedSequence:R-RNO-6803474] Esrp2 [nucleoplasm] [Complex:R-RNO-6803505] hnRNPH1:hnPNPF:RBFOX2 [nucleoplasm] [EntityWithAccessionedSequence:R-RNO-71949] HNRNPM [nucleoplasm] [DefinedSet:R-RNO-6803501] TIA1/TIAL1 [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	ESRP1 and 2 bind FGFR2 pre-mRNA to promote FGFR2b maturation and expression
output	[Complex:R-RNO-6803525] FGFR2 IIIb-specific splicing complex [nucleoplasm]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-6803527
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-6803529] FGFR2 alternative splicing
(inferredTo)	[Reaction:R-HSA-6803527] ESRP1 and 2 bind FGFR2 pre-mRNA to promote FGFR2b maturation and expression

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