Reactome | Nthl1 [nucleoplasm]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-RNO-110183] NTHL1:FapyA-dsDNA [nucleoplasm] - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10111540
displayName	Nthl1 [nucleoplasm]
endCoordinate	304
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-60537] NTHL1 [nucleoplasm] - Homo sapiens
maxDepth	1
name	Nthl1 NTHL1 D4A4E8
producedByEvent	[Reaction:R-RNO-110352] Displacement of NTHL1 glycosylase by APEX1 at the AP site - Rattus norvegicus
referenceEntity	[ReferenceGeneProduct:uniprot:D4A4E8] UniProt:D4A4E8
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48895] Rattus norvegicus
stId	R-RNO-60537
startCoordinate	23

(output)	[Reaction:R-RNO-110352] Displacement of NTHL1 glycosylase by APEX1 at the AP site
(activeUnit)	[CatalystActivity:10111615] oxidized purine nucleobase lesion DNA N-glycosylase activity of NTHL1:FapyA-dsDNA [nucleoplasm] [CatalystActivity:10111601] oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity of NTHL1:Cg-dsDNA [nucleoplasm] [CatalystActivity:10111608] oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity of NTHL1:DHU-dsDNA [nucleoplasm] [CatalystActivity:10111594] oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity of NTHL1:Tg-dsDNA [nucleoplasm]
(hasComponent)	[Complex:R-RNO-110183] NTHL1:FapyA-dsDNA [nucleoplasm] [Complex:R-RNO-110179] NTHL1:Cg-dsDNA [nucleoplasm] [Complex:R-RNO-110181] NTHL1:DHU-dsDNA [nucleoplasm] [Complex:R-RNO-110193] NTHL1:AP-dsDNA [nucleoplasm] [Complex:R-RNO-110177] NTHL1:Tg-dsDNA [nucleoplasm]
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-60537] NTHL1 [nucleoplasm]