Reactome | GG-NER incision complex:5'-incised damaged DNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm]

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GG-NER incision complex:5'-incised damaged DNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] Show undefined attributes

catalystActivities	[CatalystActivity:10185826] DNA endonuclease activity of GG-NER incision complex:5'-incised damaged DNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
consumedByEvent	[Reaction:R-RNO-5690988] 3'-incision of DNA by ERCC5 (XPG) in GG-NER - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10185562
displayName	GG-NER incision complex:5'-incised damaged DNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm]
hasComponent	[Complex:R-RNO-6790530] (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] [EntityWithAccessionedSequence:R-RNO-5688916] Chd1l [nucleoplasm] [OtherEntity:R-ALL-5691056] damaged DNA with 5' incision [nucleoplasm] [Complex:R-RNO-109943] ERCC1:ERCC4 [nucleoplasm] [EntityWithAccessionedSequence:R-RNO-67447] ERCC5 [nucleoplasm] [Complex:R-RNO-5651709] PAR-PARP1,PAR-PARP2 dimers [nucleoplasm] [Complex:R-RNO-5696649] PAR-UV-DDB [nucleoplasm] [Complex:R-RNO-5689624] TFIIH Core [nucleoplasm] [EntityWithAccessionedSequence:R-RNO-67437] Xpa [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-5690214] GG-NER incision complex:5'-incised damaged DNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] - Homo sapiens
maxDepth	8
name	GG-NER incision complex:5'-incised damaged DNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC
producedByEvent	[Reaction:R-RNO-5690213] DNA polymerases delta, epsilon or kappa bind the GG-NER site - Rattus norvegicus
schemaClass	Complex
species	[Species:48895] Rattus norvegicus
stId	R-RNO-5690214
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Referrals

(input)	[Reaction:R-RNO-5690988] 3'-incision of DNA by ERCC5 (XPG) in GG-NER
(physicalEntity)	[CatalystActivity:10185826] DNA endonuclease activity of GG-NER incision complex:5'-incised damaged DNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm]
(output)	[Reaction:R-RNO-5690213] DNA polymerases delta, epsilon or kappa bind the GG-NER site
(inferredTo)	[Complex:R-HSA-5690214] GG-NER incision complex:5'-incised damaged DNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm]

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