Reactome | phospho-Mapkapk5 [cytosol]

Schema > EntityWithAccessionedSequence > Entries

catalystActivities	[CatalystActivity:10184372] protein serine/threonine kinase activity of p-T182 MAPKAPK5 [cytosol]
compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-RNO-5690243] p-T182 MAPKAPK5:DNAJB1 [cytosol] - Rattus norvegicus [Complex:R-RNO-5692713] p-KALRN:p-S189 MAPK6:p-T182 MAPKAPK5 [cytosol] - Rattus norvegicus [Complex:R-RNO-5692723] KALRN:p-S189 MAPK6:p-T182 MAPKAPK5 [cytosol] - Rattus norvegicus
consumedByEvent	[Reaction:R-RNO-5690245] p-T182 MAPKAPK5 binds DNAJB1 - Rattus norvegicus [Reaction:R-RNO-5692781] p-S189 MAPK6:p-T182 MAPKAPK5 bind KALRN - Rattus norvegicus [Reaction:R-RNO-5692770] SEPT7 binds p-S189 MAPK6 and p-T182 MAPKAPK5 - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10184371
displayName	phospho-Mapkapk5 [cytosol]
endCoordinate	473
hasModifiedResidue	[ModifiedResidue:10169668] O-phospho-L-threonine at 182 (in Homo sapiens)
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-5687004] p-T182 MAPKAPK5 [cytosol] - Homo sapiens
maxDepth	1
name	phospho-Mapkapk5 p-T182 MAPKAPK5 F1LN87
producedByEvent	[BlackBoxEvent:R-RNO-5687120] p-S MAPK6,4:p-T182 MAPKAPK5 translocate to the cytosol - Rattus norvegicus
referenceEntity	[ReferenceGeneProduct:uniprot:F1LN87] UniProt:F1LN87
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48895] Rattus norvegicus
stId	R-RNO-5687004
startCoordinate	1

(input)	[Reaction:R-RNO-5692781] p-S189 MAPK6:p-T182 MAPKAPK5 bind KALRN [Reaction:R-RNO-5692770] SEPT7 binds p-S189 MAPK6 and p-T182 MAPKAPK5 [Reaction:R-RNO-5690245] p-T182 MAPKAPK5 binds DNAJB1
(activeUnit)	[CatalystActivity:10186188] protein serine/threonine kinase activity of KALRN:p-S189 MAPK6:p-T182 MAPKAPK5 [cytosol]
(hasComponent)	[Complex:R-RNO-5692713] p-KALRN:p-S189 MAPK6:p-T182 MAPKAPK5 [cytosol] [Complex:R-RNO-5692723] KALRN:p-S189 MAPK6:p-T182 MAPKAPK5 [cytosol] [Complex:R-RNO-5692718] SEPT7:p-S189 MAPK6:p-T182 MAPKAPK5 [cytosol] [Complex:R-RNO-5690246] p-T182 MAPKAPK5:p-S149,S151, S171 DNAJB1 [cytosol] [Complex:R-RNO-5690243] p-T182 MAPKAPK5:DNAJB1 [cytosol]
(physicalEntity)	[CatalystActivity:10184372] protein serine/threonine kinase activity of p-T182 MAPKAPK5 [cytosol]
(output)	[BlackBoxEvent:R-RNO-5687120] p-S MAPK6,4:p-T182 MAPKAPK5 translocate to the cytosol
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-5687004] p-T182 MAPKAPK5 [cytosol]