Reactome | G6B binds PTPN6,PTPN11

Schema > Reaction > Entries

category	binding
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10183669
displayName	G6B binds PTPN6,PTPN11
eventOf	[Pathway:R-RNO-114604] GPVI-mediated activation cascade - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-5684169] G6B binds PTPN6,PTPN11 - Homo sapiens
input	[EntityWithAccessionedSequence:R-RNO-5684158] Mpig6b [plasma membrane] [DefinedSet:R-RNO-389744] PTPN6,PTPN11 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	G6B binds PTPN6,PTPN11
output	[Complex:R-RNO-5684187] G6B:PTPN6,PTPN11 [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-5684169
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-RNO-114604] GPVI-mediated activation cascade
(inferredTo)	[Reaction:R-HSA-5684169] G6B binds PTPN6,PTPN11

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