Reactome | AMBRA1:DYNLL1,DYNLL2 binds BECN1 complex

Schema > Reaction > Entries

AMBRA1:DYNLL1,DYNLL2 binds BECN1 complex Show undefined attributes

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10182976
displayName	AMBRA1:DYNLL1,DYNLL2 binds BECN1 complex
eventOf	[Pathway:R-RNO-1632852] Macroautophagy - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-RNO-1632857] ULK1 phosphorylates AMBRA1:BECN1 complex - Rattus norvegicus
inferredFrom	[Reaction:R-HSA-5678313] AMBRA1:DYNLL1,DYNLL2 binds BECN1 complex - Homo sapiens
input	[Complex:R-RNO-1632839] AMBRA1:DYNLL1,DYNLL2 [cytosol] [Complex:R-RNO-5676032] BECN1 complex [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	AMBRA1:DYNLL1,DYNLL2 binds BECN1 complex
output	[Complex:R-RNO-5678311] AMBRA1:DYNLL1,DYNLL2:BECN1 complex [cytosol]
precedingEvent	[Reaction:R-RNO-5678315] BECN1 complex, p-AMBRA1 dissociate from DYNLL1,DYNLL2 - Rattus norvegicus [Reaction:R-RNO-1632843] AMBRA1 binds DYNLL1,DYNLL2 - Rattus norvegicus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-5678313
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-1632852] Macroautophagy
(precedingEvent)	[Reaction:R-RNO-1632857] ULK1 phosphorylates AMBRA1:BECN1 complex
(inferredTo)	[Reaction:R-HSA-5678313] AMBRA1:DYNLL1,DYNLL2 binds BECN1 complex

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