Reactome | Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2

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Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 Show undefined attributes

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10181736
displayName	Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2
eventOf	[Pathway:R-RNO-5663220] RHO GTPases Activate Formins - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-5666169] Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 - Homo sapiens
input	[Complex:R-RNO-375305] Kinetochore [cytosol] 15 × [Complex:R-RNO-190599] Microtubule [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2
output	[Complex:R-RNO-375303] Microtubule-bound kinetochore [cytosol]
regulatedBy	[PositiveRegulation:10181737] Positive regulation by 'Kinetochore:CDC42:GTP:p-S196-DIAPH2-2 [cytosol]'
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-5666169
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-5663220] RHO GTPases Activate Formins
(inferredTo)	[Reaction:R-HSA-5666169] Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2

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