Reactome | Microtubule [cytosol]

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Microtubule [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-RNO-2213219] Kinesins:Dynactin:microtubule [cytosol] - Rattus norvegicus [Complex:R-RNO-445022] AP2 clathrin:L1:KIF4:microtubule [cytosol] - Rattus norvegicus [Complex:R-RNO-5672333] RAC1,CDC42:GTP:IQGAP1:CLIP1:microtubule [plasma membrane] - Rattus norvegicus [Complex:R-RNO-2467806] Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] - Rattus norvegicus [Complex:R-RNO-2467806] Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] - Rattus norvegicus [Complex:R-RNO-2467806] Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] - Rattus norvegicus [Complex:R-RNO-2467806] Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] - Rattus norvegicus [Complex:R-RNO-2467806] Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] - Rattus norvegicus [Complex:R-RNO-2467806] Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] - Rattus norvegicus [Complex:R-RNO-2467806] Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] - Rattus norvegicus [Complex:R-RNO-2467806] Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] - Rattus norvegicus [Complex:R-RNO-2467806] Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] - Rattus norvegicus [Complex:R-RNO-2467806] Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] - Rattus norvegicus [Complex:R-RNO-2467806] Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] - Rattus norvegicus [Complex:R-RNO-2467806] Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] - Rattus norvegicus [Complex:R-RNO-2467806] Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] - Rattus norvegicus [Complex:R-RNO-2467806] Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] - Rattus norvegicus [Complex:R-RNO-2467806] Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] - Rattus norvegicus [Complex:R-RNO-2467806] Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] - Rattus norvegicus [Complex:R-RNO-2467806] Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] - Rattus norvegicus [Complex:R-RNO-2467806] Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] - Rattus norvegicus [Complex:R-RNO-2467806] Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] - Rattus norvegicus [Complex:R-RNO-2467806] Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] - Rattus norvegicus [Complex:R-RNO-2467806] Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] - Rattus norvegicus [Complex:R-RNO-2467806] Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] - Rattus norvegicus [Complex:R-RNO-2467806] Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] - Rattus norvegicus [Complex:R-RNO-2467806] Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] - Rattus norvegicus [Complex:R-RNO-2467806] Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] - Rattus norvegicus [Complex:R-RNO-2467806] Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] - Rattus norvegicus [Complex:R-RNO-2467806] Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] - Rattus norvegicus [Complex:R-RNO-2467806] Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] - Rattus norvegicus [Complex:R-RNO-2467806] Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] - Rattus norvegicus [Complex:R-RNO-2467806] Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] - Rattus norvegicus
consumedByEvent	[Reaction:R-RNO-8867370] TTLL3, TTLL8, TTLL10 polyglycylate tubulin - Rattus norvegicus [Reaction:R-RNO-8865774] TTLLs polyglutamylate tubulin - Rattus norvegicus [Reaction:R-RNO-380316] Association of NuMA with microtubules - Rattus norvegicus [Reaction:R-RNO-9668419] SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites - Rattus norvegicus [Reaction:R-RNO-5618328] ATAT acetylates microtubules - Rattus norvegicus [Reaction:R-RNO-983266] Kinesins bind microtubules - Rattus norvegicus [Reaction:R-RNO-8852280] GTSE1 binds microtubule lattice in interphase cells - Rattus norvegicus [Reaction:R-RNO-9648017] EML4 binds to microtubules - Rattus norvegicus [Reaction:R-RNO-375302] Kinetochore capture of astral microtubules - Rattus norvegicus [Reaction:R-RNO-375302] Kinetochore capture of astral microtubules - Rattus norvegicus [Reaction:R-RNO-375302] Kinetochore capture of astral microtubules - Rattus norvegicus [Reaction:R-RNO-375302] Kinetochore capture of astral microtubules - Rattus norvegicus [Reaction:R-RNO-375302] Kinetochore capture of astral microtubules - Rattus norvegicus [Reaction:R-RNO-375302] Kinetochore capture of astral microtubules - Rattus norvegicus [Reaction:R-RNO-375302] Kinetochore capture of astral microtubules - Rattus norvegicus [Reaction:R-RNO-375302] Kinetochore capture of astral microtubules - Rattus norvegicus [Reaction:R-RNO-375302] Kinetochore capture of astral microtubules - Rattus norvegicus [Reaction:R-RNO-375302] Kinetochore capture of astral microtubules - Rattus norvegicus [Reaction:R-RNO-375302] Kinetochore capture of astral microtubules - Rattus norvegicus [Reaction:R-RNO-375302] Kinetochore capture of astral microtubules - Rattus norvegicus [Reaction:R-RNO-375302] Kinetochore capture of astral microtubules - Rattus norvegicus [Reaction:R-RNO-375302] Kinetochore capture of astral microtubules - Rattus norvegicus [Reaction:R-RNO-375302] Kinetochore capture of astral microtubules - Rattus norvegicus [Reaction:R-RNO-5666169] Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 - Rattus norvegicus [Reaction:R-RNO-5666169] Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 - Rattus norvegicus [Reaction:R-RNO-5666169] Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 - Rattus norvegicus [Reaction:R-RNO-5666169] Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 - Rattus norvegicus [Reaction:R-RNO-5666169] Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 - Rattus norvegicus [Reaction:R-RNO-5666169] Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 - Rattus norvegicus [Reaction:R-RNO-5666169] Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 - Rattus norvegicus [Reaction:R-RNO-5666169] Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 - Rattus norvegicus [Reaction:R-RNO-5666169] Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 - Rattus norvegicus [Reaction:R-RNO-5666169] Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 - Rattus norvegicus [Reaction:R-RNO-5666169] Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 - Rattus norvegicus [Reaction:R-RNO-5666169] Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 - Rattus norvegicus [Reaction:R-RNO-5666169] Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 - Rattus norvegicus [Reaction:R-RNO-5666169] Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 - Rattus norvegicus [Reaction:R-RNO-5666169] Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 - Rattus norvegicus [Reaction:R-RNO-190520] Association of Golgi transport vesicles with microtubules - Rattus norvegicus [Reaction:R-RNO-5672329] IQGAP1 binds CLIP1 and microtubules - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10121548
displayName	Microtubule [cytosol]
hasComponent	13 × [Polymer:R-RNO-8982424] Microtubule protofilament [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-9833607] microtubule (no TUBA4B) [cytosol] - Homo sapiens [Complex:R-HSA-190599] Microtubule [cytosol] - Homo sapiens
maxDepth	6
name	Microtubule
producedByEvent	[Reaction:R-RNO-9646685] Aggresome dissociates from dynein and microtubule - Rattus norvegicus [Reaction:R-RNO-9836404] p-PKR dimer phosphorylates MAPT - Rattus norvegicus [Reaction:R-RNO-445071] Reinsertion of L1 into the plasma membrane - Rattus norvegicus
schemaClass	Complex
species	[Species:48895] Rattus norvegicus
stId	R-RNO-190599
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Referrals

(input)	[Reaction:R-RNO-5618328] ATAT acetylates microtubules [Reaction:R-RNO-8867370] TTLL3, TTLL8, TTLL10 polyglycylate tubulin [Reaction:R-RNO-8865774] TTLLs polyglutamylate tubulin [Reaction:R-RNO-983266] Kinesins bind microtubules [Reaction:R-RNO-5672329] IQGAP1 binds CLIP1 and microtubules [Reaction:R-RNO-8852280] GTSE1 binds microtubule lattice in interphase cells [Reaction:R-RNO-380316] Association of NuMA with microtubules [Reaction:R-RNO-9648017] EML4 binds to microtubules [Reaction:R-RNO-375302] Kinetochore capture of astral microtubules [Reaction:R-RNO-9668419] SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites [Reaction:R-RNO-5666169] Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 [Reaction:R-RNO-190520] Association of Golgi transport vesicles with microtubules
(inferredTo)	[Complex:R-HSA-9833607] microtubule (no TUBA4B) [cytosol] [Complex:R-HSA-190599] Microtubule [cytosol]
(hasComponent)	[Complex:R-RNO-2213219] Kinesins:Dynactin:microtubule [cytosol] [Complex:R-RNO-983245] Kinesins:microtubule [cytosol] [Complex:R-RNO-445022] AP2 clathrin:L1:KIF4:microtubule [cytosol] [Complex:R-RNO-5672333] RAC1,CDC42:GTP:IQGAP1:CLIP1:microtubule [plasma membrane] [Complex:R-RNO-2029135] Dynein:Dynactin:microtubule [cytosol] [Complex:R-RNO-8852286] GTSE1:microtubule [cytosol] [Complex:R-RNO-8852300] MAPRE1:microtubule plus end [cytosol] [Complex:R-RNO-379273] Mature centrosome:nucleated microtubules [cytosol] [Complex:R-RNO-9648023] EML4 homotrimer:Microtubule [cytosol] [Complex:R-RNO-2484819] Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] [Complex:R-RNO-2484902] Sister Centromere:Kinetochore:Microtubules [cytosol] [Complex:R-RNO-2467806] Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] [Complex:R-RNO-9619556] MAPT-8:Microtubule [cytosol] [Complex:R-RNO-375303] Microtubule-bound kinetochore [cytosol] [Complex:R-RNO-190556] connexons in Golgi transport vesicle docked to microtubules [Golgi-associated vesicle membrane] [Complex:R-RNO-9646389] PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex [microtubule organizing center]
(output)	[Reaction:R-RNO-445071] Reinsertion of L1 into the plasma membrane [Reaction:R-RNO-9836404] p-PKR dimer phosphorylates MAPT [Reaction:R-RNO-9646685] Aggresome dissociates from dynein and microtubule

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