Reactome | UBE2L6:TRIM25 [nucleoplasm]

Schema > Complex > Entries

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-RNO-5653760] UBE2L6:TRIM25:DNA polymerase Y:MonoUb:K164-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] - Rattus norvegicus
consumedByEvent	[Reaction:R-RNO-5653756] TRIM25 binds monoUb:164-PCNA - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10180601
displayName	UBE2L6:TRIM25 [nucleoplasm]
hasComponent	[EntityWithAccessionedSequence:R-RNO-5653667] Trim25 [nucleoplasm] [EntityWithAccessionedSequence:R-RNO-5653666] Ube2l6 [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-5653664] UBE2L6:TRIM25 [nucleoplasm] - Homo sapiens
maxDepth	2
name	UBE2L6:TRIM25
producedByEvent	[Reaction:R-RNO-5653754] UBE2L6:TRIM25 ISGylates monoUb:K164-PCNA - Rattus norvegicus
schemaClass	Complex
species	[Species:48895] Rattus norvegicus
stId	R-RNO-5653664
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(output)	[Reaction:R-RNO-5653754] UBE2L6:TRIM25 ISGylates monoUb:K164-PCNA
(activeUnit)	[CatalystActivity:10180623] ISG15 transferase activity of UBE2L6:TRIM25:DNA polymerase Y:MonoUb:K164-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm]
(input)	[Reaction:R-RNO-5653756] TRIM25 binds monoUb:164-PCNA
(hasComponent)	[Complex:R-RNO-5653760] UBE2L6:TRIM25:DNA polymerase Y:MonoUb:K164-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm]
(inferredTo)	[Complex:R-HSA-5653664] UBE2L6:TRIM25 [nucleoplasm]