Reactome | GPR161 is internalized

Schema > BlackBoxEvent > Entries

category	omitted
compartment	[Compartment:261122] ciliary membrane [Compartment:24337] endocytic vesicle membrane
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10180109
displayName	GPR161 is internalized
eventOf	[Pathway:R-RNO-5632684] Hedgehog 'on' state - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[BlackBoxEvent:R-HSA-5635102] GPR161 is internalized - Homo sapiens
input	[EntityWithAccessionedSequence:R-RNO-5610373] Gpr161 [ciliary membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	GPR161 is internalized
output	[EntityWithAccessionedSequence:R-RNO-5635021] Gpr161 [endocytic vesicle membrane]
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:48895] Rattus norvegicus
stId	R-RNO-5635102
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-RNO-5632684] Hedgehog 'on' state
(inferredTo)	[BlackBoxEvent:R-HSA-5635102] GPR161 is internalized

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