Reactome | RAB3IP stimulates nucleotide exchange on RAB8A

Schema > Reaction > Entries

RAB3IP stimulates nucleotide exchange on RAB8A Show undefined attributes

catalystActivity	[CatalystActivity:10179032] guanyl-nucleotide exchange factor activity of RAB8A:GDP:RAB3IP:RAB11A:GTP:FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane]
category	transition
compartment	[Compartment:20699] Golgi membrane
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10179034
displayName	RAB3IP stimulates nucleotide exchange on RAB8A
eventOf	[Pathway:R-RNO-5620916] VxPx cargo-targeting to cilium - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[BlackBoxEvent:R-RNO-5623525] Cargo-carrying vesicles bud from the TGN - Rattus norvegicus
inferredFrom	[Reaction:R-HSA-5623521] RAB3IP stimulates nucleotide exchange on RAB8A - Homo sapiens
input	[SimpleEntity:R-ALL-29438] GTP [cytosol] [Complex:R-RNO-5623444] RAB8A:GDP:RAB3IP:RAB11A:GTP:FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	RAB3IP stimulates nucleotide exchange on RAB8A
output	[SimpleEntity:R-ALL-29420] GDP [cytosol] [Complex:R-RNO-5623447] RAB8A:GTP:RAB3IP:RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane]
precedingEvent	[Reaction:R-RNO-5623519] RAB3IP and RAB8A bind to the ciliary targeting complex - Rattus norvegicus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-5623521
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-5620916] VxPx cargo-targeting to cilium
(precedingEvent)	[BlackBoxEvent:R-RNO-5623525] Cargo-carrying vesicles bud from the TGN
(inferredTo)	[Reaction:R-HSA-5623521] RAB3IP stimulates nucleotide exchange on RAB8A