Reactome | K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex [cytosol]

Schema > Complex > Entries

compartment	[Compartment:70101] cytosol
consumedByEvent	[BlackBoxEvent:R-RNO-5607724] 26S proteasome processes K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex to form NF-kB complex - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10177997
displayName	K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex [cytosol]
hasComponent	[Complex:R-RNO-194043] NFKB1(1-433):RELA [cytosol] [EntityWithAccessionedSequence:R-RNO-1168581] phospho-Nfkbia [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-5607697] K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex [cytosol] - Homo sapiens
maxDepth	3
name	K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex
producedByEvent	[BlackBoxEvent:R-RNO-5607728] beta-TRCP ubiquitinates IkB-alpha in p-S32,33-IkB-alpha:NF-kB complex - Rattus norvegicus
schemaClass	Complex
species	[Species:48895] Rattus norvegicus
stId	R-RNO-5607697
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[BlackBoxEvent:R-RNO-5607724] 26S proteasome processes K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex to form NF-kB complex
(output)	[BlackBoxEvent:R-RNO-5607728] beta-TRCP ubiquitinates IkB-alpha in p-S32,33-IkB-alpha:NF-kB complex
(inferredTo)	[Complex:R-HSA-5607697] K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex [cytosol]

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