Reactome | SCF-beta-TRCP [cytosol]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10178013] ubiquitin-protein transferase activity of SCF-beta-TRCP [cytosol]
compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-RNO-5607693] Active NIK:p-176,S180-IKKA dimer:p-7S-p100:SCF-beta-TRCP [cytosol] - Rattus norvegicus
consumedByEvent	[Reaction:R-RNO-5607723] SCF-beta-TRCP binds p-7S-p100 in active NIK:p-S176,180-IKKA dimer:p-7S-p100:RELB - Rattus norvegicus [BlackBoxEvent:R-RNO-5607728] beta-TRCP ubiquitinates IkB-alpha in p-S32,33-IkB-alpha:NF-kB complex - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10177991
displayName	SCF-beta-TRCP [cytosol]
hasComponent	[DefinedSet:R-RNO-5607666] beta-TrCP [cytosol] [EntityWithAccessionedSequence:R-RNO-174230] Cul1 [cytosol] [EntityWithAccessionedSequence:R-RNO-174150] Skp1 [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-5607687] SCF-beta-TRCP [cytosol] - Homo sapiens
maxDepth	3
name	SCF-beta-TRCP
producedByEvent	[BlackBoxEvent:R-RNO-5607728] beta-TRCP ubiquitinates IkB-alpha in p-S32,33-IkB-alpha:NF-kB complex - Rattus norvegicus [BlackBoxEvent:R-RNO-5607725] SCF-beta-TRCP ubiquitinates p-7S-p100:RELB in active NIK:p-176,S180-IKKA dimer:p-7S-p100:SCF-beta-TRCP - Rattus norvegicus
schemaClass	Complex
species	[Species:48895] Rattus norvegicus
stId	R-RNO-5607687
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-RNO-5607723] SCF-beta-TRCP binds p-7S-p100 in active NIK:p-S176,180-IKKA dimer:p-7S-p100:RELB [BlackBoxEvent:R-RNO-5607728] beta-TRCP ubiquitinates IkB-alpha in p-S32,33-IkB-alpha:NF-kB complex
(output)	[BlackBoxEvent:R-RNO-5607725] SCF-beta-TRCP ubiquitinates p-7S-p100:RELB in active NIK:p-176,S180-IKKA dimer:p-7S-p100:SCF-beta-TRCP [BlackBoxEvent:R-RNO-5607728] beta-TRCP ubiquitinates IkB-alpha in p-S32,33-IkB-alpha:NF-kB complex
(activeUnit)	[CatalystActivity:10178005] ubiquitin-protein transferase activity of Active NIK:p-176,S180-IKKA dimer:p-7S-p100:SCF-beta-TRCP [cytosol]
(hasComponent)	[Complex:R-RNO-5607693] Active NIK:p-176,S180-IKKA dimer:p-7S-p100:SCF-beta-TRCP [cytosol]
(physicalEntity)	[CatalystActivity:10178013] ubiquitin-protein transferase activity of SCF-beta-TRCP [cytosol]
(inferredTo)	[Complex:R-HSA-5607687] SCF-beta-TRCP [cytosol]

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