Reactome | Activated protein C binds Protein S

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Activated protein C binds Protein S Show undefined attributes

category	binding
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10177914
displayName	Activated protein C binds Protein S
eventOf	[Pathway:R-RNO-9769739] Regulation of clotting cascade - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-5604929] Activated protein C binds Protein S - Homo sapiens
input	[Complex:R-RNO-141050] Activated protein C [extracellular region] [EntityWithAccessionedSequence:R-RNO-141004] Pros1 [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	Activated protein C binds Protein S
output	[Complex:R-RNO-5604926] Activated protein C:Protein S [plasma membrane]
precedingEvent	[Reaction:R-RNO-5603467] Activated protein C is released from PROCR - Rattus norvegicus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-5604929
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-9769739] Regulation of clotting cascade
(inferredTo)	[Reaction:R-HSA-5604929] Activated protein C binds Protein S

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