Reactome | p-PKC [cytosol]

Schema > DefinedSet > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-RNO-5218773] DAG:active PKC:Ca+2 [plasma membrane] - Rattus norvegicus
consumedByEvent	[Reaction:R-RNO-5218813] DAG and Ca+2 bind to PKC and tether it to membrane - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10175187
displayName	p-PKC [cytosol]
hasMember	[EntityWithAccessionedSequence:R-RNO-5218698] phospho-p-T410,T563-PRKCZ [cytosol] - Rattus norvegicus [EntityWithAccessionedSequence:R-RNO-5218706] phospho-p-T500,T642,S661-PRKCB [cytosol] - Rattus norvegicus [EntityWithAccessionedSequence:R-RNO-5218734] phospho-p-T507,S645,S664-PRKCD [cytosol] - Rattus norvegicus [EntityWithAccessionedSequence:R-RNO-4332337] phospho-p-T497,T638,S657-PRKCA [cytosol] - Rattus norvegicus
inDisease	false
inferredFrom	[DefinedSet:R-HSA-5218758] p-PKC [cytosol] - Homo sapiens
maxDepth	2
name	p-PKC p-PKCA, p-PKCB, p-PKCD, p-PKCZ
producedByEvent	[Reaction:R-RNO-5218805] PKC autophosphorylates - Rattus norvegicus
schemaClass	DefinedSet
species	[Species:48895] Rattus norvegicus
stId	R-RNO-5218758

(activeUnit)	[CatalystActivity:10175297] calcium,diacylglycerol-dependent serine/threonine kinase activity of DAG:active PKC:Ca+2 [plasma membrane]
(input)	[Reaction:R-RNO-5218813] DAG and Ca+2 bind to PKC and tether it to membrane
(output)	[Reaction:R-RNO-5218805] PKC autophosphorylates
(hasComponent)	[Complex:R-RNO-5218773] DAG:active PKC:Ca+2 [plasma membrane]
(inferredTo)	[DefinedSet:R-HSA-5218758] p-PKC [cytosol]