Reactome | Pink1 is recruited from the cytoplasm to the mitochondria

Schema > Reaction > Entries

Pink1 is recruited from the cytoplasm to the mitochondria Show undefined attributes

catalystActivity	[CatalystActivity:10174885] protein transmembrane transporter activity of TOMM40 Complex [mitochondrial outer membrane]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10174887
displayName	Pink1 is recruited from the cytoplasm to the mitochondria
eventOf	[Pathway:R-RNO-5205685] PINK1-PRKN Mediated Mitophagy - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-RNO-5205681] Pink1 is cleaved on healthy mitochondria - Rattus norvegicus [Reaction:R-RNO-5205672] Uncleaved Pink1 accumulates in damaged mitochondria - Rattus norvegicus
inferredFrom	[Reaction:R-HSA-5205661] Pink1 is recruited from the cytoplasm to the mitochondria - Homo sapiens
input	[EntityWithAccessionedSequence:R-RNO-5205637] PINK1 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Pink1 is recruited from the cytoplasm to the mitochondria
output	[EntityWithAccessionedSequence:R-RNO-5205671] PINK1 [mitochondrial intermembrane space]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-5205661
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-5205685] PINK1-PRKN Mediated Mitophagy
(precedingEvent)	[Reaction:R-RNO-5205681] Pink1 is cleaved on healthy mitochondria [Reaction:R-RNO-5205672] Uncleaved Pink1 accumulates in damaged mitochondria
(inferredTo)	[Reaction:R-HSA-5205661] Pink1 is recruited from the cytoplasm to the mitochondria

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