Reactome | p-Y348-SYK dissociates

Schema > Reaction > Entries

p-Y348-SYK dissociates Show undefined attributes

category	dissociation
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10142293
displayName	p-Y348-SYK dissociates
eventOf	[Pathway:R-RNO-114604] GPVI-mediated activation cascade - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-RNO-434836] Syk/Lck phosphorylate LAT - Rattus norvegicus [Reaction:R-RNO-429449] Syk activation leads to SLP-76 activation - Rattus norvegicus
inferredFrom	[Reaction:R-HSA-453183] p-Y348-SYK dissociates - Homo sapiens
input	[Complex:R-RNO-453171] GPVI:phosphorylated Fc Epsilon R1 gamma:FYN:LYN:Collagen type I:p-Y348-SYK [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	p-Y348-SYK dissociates
output	[Complex:R-RNO-434822] GPVI:phosphorylated Fc Epsilon R1 gamma:FYN:LYN:Collagen type I [plasma membrane] [EntityWithAccessionedSequence:R-RNO-437953] phospho-p-Y348-SYK [cytosol]
precedingEvent	[Reaction:R-RNO-453200] SYK autophosphorylates - Rattus norvegicus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-453183
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-114604] GPVI-mediated activation cascade
(precedingEvent)	[Reaction:R-RNO-434836] Syk/Lck phosphorylate LAT [Reaction:R-RNO-429449] Syk activation leads to SLP-76 activation
(inferredTo)	[Reaction:R-HSA-453183] p-Y348-SYK dissociates