Reactome | VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-RNO-5218635] VEGFA:p-6Y-VEGFR2:p-SHB:p-5Y-PTK2 [plasma membrane] - Rattus norvegicus [Complex:R-RNO-4420141] VEGFA:p-6Y-VEGFR2:p-SHB:PTK2 [plasma membrane] - Rattus norvegicus
consumedByEvent	[Reaction:R-RNO-4420083] PTK2 binds p-S-SHB and is recruited to p-6Y-VEGFR2 - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10172394
displayName	VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane]
hasComponent	[EntityWithAccessionedSequence:R-RNO-5228991] phospho-Shb [cytosol] [Complex:R-RNO-4420101] VEGFA dimer:p-6Y-VEGFR2 dimer [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-4420164] VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane] - Homo sapiens
maxDepth	4
name	VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB
producedByEvent	[Reaction:R-RNO-4420128] SRC-1 phosphorylates SHB - Rattus norvegicus
schemaClass	Complex
species	[Species:48895] Rattus norvegicus
stId	R-RNO-4420164
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(hasComponent)	[Complex:R-RNO-5218635] VEGFA:p-6Y-VEGFR2:p-SHB:p-5Y-PTK2 [plasma membrane] [Complex:R-RNO-4420141] VEGFA:p-6Y-VEGFR2:p-SHB:PTK2 [plasma membrane] [Complex:R-RNO-5218639] VEGFA:p-6Y-VEGFR2:p-SHB:p-Y397-PTK2 [plasma membrane] [Complex:R-RNO-5218771] VEGFA:p-6Y-VEGFR2:pS-SHB:p-5Y,S732-PTK2 [plasma membrane] [Complex:R-RNO-5218760] VEGFA:p-6Y-VEGFR2:p-SHB:p-6Y,S732-PTK2 [plasma membrane]
(input)	[Reaction:R-RNO-4420083] PTK2 binds p-S-SHB and is recruited to p-6Y-VEGFR2
(output)	[Reaction:R-RNO-4420128] SRC-1 phosphorylates SHB
(inferredTo)	[Complex:R-HSA-4420164] VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane]