Reactome | PTK2 binds p-S-SHB and is recruited to p-6Y-VEGFR2

Schema > Reaction > Entries

PTK2 binds p-S-SHB and is recruited to p-6Y-VEGFR2 Show undefined attributes

category	binding
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:9979708] Wright, Adam, 2024-03-07
dbId	10050816
displayName	PTK2 binds p-S-SHB and is recruited to p-6Y-VEGFR2
eventOf	[Pathway:R-RNO-4420097] VEGFA-VEGFR2 Pathway - Rattus norvegicus
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
followingEvent	[Reaction:R-RNO-5218642] PTK2 autophosphorylates - Rattus norvegicus
inferredFrom	[Reaction:R-HSA-4420083] PTK2 binds p-S-SHB and is recruited to p-6Y-VEGFR2 - Homo sapiens
input	[EntityWithAccessionedSequence:R-RNO-201621] PTK2 [cytosol] [Complex:R-RNO-4420164] VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane]
isInDisease	false
isInferred	true
name	PTK2 binds p-S-SHB and is recruited to p-6Y-VEGFR2
output	[Complex:R-RNO-4420141] VEGFA:p-6Y-VEGFR2:p-SHB:PTK2 [plasma membrane]
precedingEvent	[Reaction:R-RNO-4420128] SRC-1 phosphorylates SHB - Rattus norvegicus
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-4420083
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-4420097] VEGFA-VEGFR2 Pathway
(precedingEvent)	[Reaction:R-RNO-5218642] PTK2 autophosphorylates
(inferredTo)	[Reaction:R-HSA-4420083] PTK2 binds p-S-SHB and is recruited to p-6Y-VEGFR2

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