Reactome | CASR binds Ca2+

Schema > Reaction > Entries

category	binding
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10137413
displayName	CASR binds Ca2+
eventOf	[Pathway:R-RNO-420499] Class C/3 (Metabotropic glutamate/pheromone receptors) - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-420724] CASR binds Ca2+ - Homo sapiens
input	[SimpleEntity:R-ALL-74112] Ca2+ [extracellular region] [EntityWithAccessionedSequence:R-RNO-420719] CASR [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	CASR binds Ca2+ Calcium-sensing receptor binds calcium
output	[Complex:R-RNO-420743] CASR:Ca2+ [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-420724
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-RNO-420499] Class C/3 (Metabotropic glutamate/pheromone receptors)
(inferredTo)	[Reaction:R-HSA-420724] CASR binds Ca2+

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