Reactome | GIT1 binds bPIX

Schema > Reaction > Entries

GIT1 binds bPIX Show undefined attributes

category	binding
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10172350
displayName	GIT1 binds bPIX
eventOf	[Pathway:R-RNO-3928664] Ephrin signaling - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-RNO-3928633] bPIX exchanges GTP for GDP on RAC, activating it - Rattus norvegicus
inferredFrom	[Reaction:R-HSA-3928631] GIT1 binds bPIX - Homo sapiens
input	[EntityWithAccessionedSequence:R-RNO-430346] Arhgef7 [cytosol] [Complex:R-RNO-3928559] EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1 [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	GIT1 binds bPIX
output	[Complex:R-RNO-3928512] EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane]
precedingEvent	[Reaction:R-RNO-3928614] EFNB:GRB4 binds GIT1 - Rattus norvegicus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-3928631
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-3928664] Ephrin signaling
(precedingEvent)	[Reaction:R-RNO-3928633] bPIX exchanges GTP for GDP on RAC, activating it
(inferredTo)	[Reaction:R-HSA-3928631] GIT1 binds bPIX